Neanderthals are in all of us: Genetic legacy of our Pleistocene ancestors broadens understanding of disease and survival

Neanderthals in all of us: Genetic legacy of our Pleistocene ancestors broadens our understanding of disease and survival
Credit: Pixabay/ kellepics

Using the new and rapidly improving ability to piece together fragments of ancient DNA, scientists are finding that traits inherited from our ancient cousins are still with us now, affecting our fertility, our immune systems, even how our bodies handled the COVID-19 virus.

“We’re now carrying the genetic legacies and learning about what that means for our bodies and our health,” said Mary Prendergast, a Rice University archeologist.

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In the past few months alone, researchers have linked Neanderthal DNA to a serious hand diseasethe shape of people’s noses and various other human traits. They even inserted a gene carried by Neanderthals and Denisovans into mice to investigate its effects on biology, and found it gave them larger heads and an extra rib.

Much of the human journey remains a mystery. But Dr. Hugo Zeberg of the Karolinska Insitute in Sweden said new technologies, research and collaborations are helping scientists begin to answer the basic but cosmic questions: “Who are we? Where did we come from?”

And the answers point to a profound reality: We have far more in common with our extinct cousins than we ever thought.

This is an excerpt. Read the full article here

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