Will eye and face transplants become more common? First recipient is making a strong recovery

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In June of 2021 Aaron James experienced a terrible accident while working as an electrical lineman. The 46-year-old military veteran and Arkansas resident lost much of the left side of his face—including his left eye—to severely disfiguring electrical burns that also destroyed his left arm.

Two years later James received the first-ever partial face and whole-eye transplant, performed by surgeons at NYU Langone Health in New York City. And now, more than a year after that, James has made a strong recovery with no evidence of tissue rejection, his medical team reported in a paper published on Monday in JAMA.

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Whole-eye transplants have long been a dream among doctors and scientists seeking to treat people with serious eye injuries or blindness. The first corneal transplant took place in 1905. But efforts to transplant an entire eye have been thwarted by the devilish difficulty of regrowing the optic nerve, which carries signals from the eye’s light-sensitive retina to the brain’s visual centers, where they are perceived as sight.

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