A single dose of psilocybin appears more effective than drugs in treating depression

magic-mushrooms-brain

A new study compares psilocybin — the active compound in magic mushrooms, with a common antidepressant medication.

  • During 6 months of follow-up, both drugs effectively improved depressive symptoms.
  • Psilocybin, however, seemed to provide additional benefits, including improved psychological connectedness and social functioning.
  • This is a small study, and scientists still need to conduct more research to understand the longterm effects of psilocybin.
Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other ‘disruptive’ innovations. Subscribe to our newsletter.
[T]hese studies identified few serious side effects, and rather than a daily dose, the treatment appears to be effective for weeks or months after just a single dose.

“The excitement is justified, given psilocybin’s potential to treat resistant depression, anxiety, and post-traumatic stress disorder (PTSD),” said [Ozan Toy, MD, a neuropsychiatrist not involved in this study]. “Many studies have demonstrated significant benefits for PTSD.”

Still, Toy added a word of caution: “Concerns remain about long-term effects, accessibility, and better safety data to understand the risks and benefits.”

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

d-b
Blocked arteries, kidney stones, nausea, constipation, fatigue: Long list of health problems caused by too much vitamin D 
Screenshot-PM-24
Viewpoint: The herbicide glyphosate isn’t perfect. Banning it would be far worse.
circular-bioeconomy-should-focus-on-sustainable-wellbeing
GLP podcast: What's wrong with 'doomsday' environmentalism? It's false.
Screenshot 2026-02-25 at 11.20
Why the herbicide glyphosate is key to sustainable agriculture
screen shot at pm
Word games: How Moderna is selling its newest vaccine without using the “v” word
ChatGPT-Image-Feb-16-2026-01_04_32-PM
Raw milk myth wake-up call
ChatGPT-Image-Apr-28-2026-12_46_14-PM-2
Kennedy has quietly stopped touting problematic raw milk. Health concerns aren’t why
ChatGPT-Image-Feb-16-2026-01_57_31-PM
Viewpoint: ‘Science-as-Satan’ unites the MAHA—MAGA movements. Is a breakup in the works?
ChatGPT-Image-Apr-22-2026-11_06_18-AM
Wellness influencer nonsense: No, nicotine does not boost cognition and productivity, but it can damage your health 
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.