1. Polio eradication
Jonas Salk had developed a polio vaccine in the early 1950’s but was struggling to find a way to test it in field trials as traditionally used rhesus monkey cells were too expensive for such a large-scale study. In 1952, HeLa cells were found to be both susceptible to, but not killed by polio, making them an ideal source of host cells.
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2. Improved cell culture practices
During the mass production and distribution of HeLa cells for polio vaccine testing at Tuskegee University, lead researchers Brown and Henderson pioneered new cell culture protocols.
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3. Chromosome counting
Rebecca Skloot describes in her book, The Immortal Life of Henrietta Lacks, how a lab mix up in Texas in 1953 accidentally enabled researchers to see and count each chromosome clearly in the HeLa cells they were working with.
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4. Genome mapping
Harris and Watkins created the first human-animal hybrids in 1965, by fusing HeLa cells with mouse cells.
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5. Human papilloma virus (HPV) vaccines
In the 1980’s, Henrietta’s cells were found to contain HPV-18 by Harald zur Hausen, who later went on to win a Nobel Prize for his discovery linking HPV and cervical cancer.
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