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How do antidepressants work? We still don’t know

Jillian Mock | 
[A]bout a third of Americans are showing signs of depression or anxiety, according to the U.S. Census Bureau. That’s about ...
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Second psychopharmacology revolution: New drugs could change the way we treat depression

Charles Zorumski, Eugene Rubin | 
The field of psychopharmacology was born during the 15 years between 1955 and 1970. Now, nearly 60 years later, the field of psychiatry may ...
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Long-term antidepressant use linked to higher risk of heart attack, stroke and death

Andrea Petersen | 
More Americans are taking antidepressant medications like Prozac and Zoloft for extended periods of time: One-quarter of people on the ...
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Can genetic testing pinpoint the right antidepressant, or is it just ‘a shot in the dark’?

Ilana Marcus | 
For patients who weren’t responding well after trying one or two different antidepressants, [physician Jeremy Bruce] started sending samples of ...
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Exercise can fight depression, but it doesn’t work for everyone

Jill Adams | 
Is there evidence to support the idea that exercise can have an effect on depression? And if so, how much ...
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Can this DNA test find the right depression medication for you?

Erin Brodwin | 
Using DNA testing to determine how well a given depression medication will work with a patient's genetic makeup is becoming ...
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Antidepressant withdrawal effects ‘severe’ for more than half of patients, study says

Christopher Lane | 
“More than half (56 percent) of people who attempt to come off antidepressants experience withdrawal effects,” assert the authors of ...
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Genetic tests are used to determine antidepressant efficacy – but science might not back up claims

Rebecca Robbins | 
It can be notoriously difficult for psychiatrists and patients to determine which antidepressant might be most effective, or which might cause side ...
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Treating autism with serotonin

Jessica Wright | 
Boosting levels of the chemical messenger serotonin makes mice that model autism more social, according to a study published [August ...
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Genetic therapies won’t solve depression anytime soon

Ben Locwin | 
Can a better understanding of the genetics of depression lead us to safer, more effective treatments for the disease? ...
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