Genetic mutation linked with typical form of migraine

The following is an excerpt.

A UC San Francisco-led research team has identified a genetic mutation that is strongly associated with a typical form of migraine.

In a paper published on May 1 in Science Translational Medicine, the team linked the mutation with evidence of migraine in humans, in a mouse model of migraine and in cell culture in the laboratory.

The mutation is in the gene known as casein kinase I delta (CKIdelta).

“This is the first gene in which mutations have been shown to cause a very typical form of migraine,” said senior investigator Louis J. Ptácek, a Howard Hughes Medical Institute investigator and a professor of neurology at UCSF. “It’s our initial glimpse into a black box that we don’t yet understand.”

View the original article here: Genetic Mutation Linked with Typical Form of Migraine

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