X chromosome may control male fertility

AAAS X chromosome
Image: Hemera/Thinkstock via Science AAAS

In the past, researchers thought the Y chromosome was what defined maleness: It contains genes that are responsible for sex determination, male development, and male fertility.

But now a team has discovered that X—the “female” chromosome—could also play a significant role in maleness. It contains scores of genes that are active only in tissue destined to become sperm. The finding shakes up our ideas about how sex chromosomes influence gender and also suggests that at least some parts of the X chromosome are playing an unexpectedly dynamic role in evolution.

Read the full article here: ‘Female’ Chromosome May Leave a Mark on Male Fertility

Additional Resources:

  • “X Marks the Spot for Sperm Production,” Scientist
    In addition to the headline-grabbing sex-linked angle, this study also revealed the surprisingly rapid evolution of genes in some regions of the X chromosome. 
  • “Y chromosome sequence completed,” Nature
    In 2003, some of the researchers who worked on this X chromosome study published work that similarly described the Y chromosome. 

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
Woman_Vaping_Electronic_Cigarette_50687233623
Trump administration clears the way for speedy approvals of once-restricted tobacco vapes and pouches
ChatGPT-Image-Sep-25-2026-11_36_56-AM
Now AI almost started a war with China
Screenshot-2026-09-17-at-1.07.08-PM
'We are dangerously addicted to antidepressants': Should we heed RFK Jr.’s sobering warning?
Screenshot-2026-09-24-at-1.24.47-PM
80% of Americans take (mostly useless) supplements for their health
ChatGPT-Image-Sep-2-2026-02_03_32-PM
How much of a problem is AI’s water use?
Screenshot-2026-09-16-at-10.27.33-AM
Viewpoint: SCOTUS poised to address First Amendment tension between mandatory vaccines, children’s health and religious freedom 
ChatGPT-Image-Sep-27-2026-10_00_17-AM
Current and future RFK Jr. aides criticize his science-rejectionist vaccine views
ChatGPT-Image-Sep-21-2026-11_54_00-AM
Viewpoint: Activist environmental NGOs are turning from public funding to activist billionaires to support their campaigns. It won’t end well.
ChatGPT-Image-Sep-23-2026-01_52_03-PM
Viewpoint: 4 very real AI doomsday scenarios
Screenshot-2026-09-16-at-2.26.42-PM
Viewpoint: How to ecologically damage America’s forests: Ban glyphosate
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.