Malaria parasites weakened through precise gene deletions could be used as a vaccine to protect against malaria infection, according to a study recently published in Vaccine.
The study followed up on previous research that tested a new malaria vaccine with parasites weakened by radiation. The trial was promising but vaccination required intravenous administration with multiple high doses. Researchers at Seattle BioMed outlined a method to attenuate the malaria parasite through genetic engineering, which could offer a consistently protective malaria vaccine.
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