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Premenstrual dysphoric disorder: Debilitating form of PMS has genetic basis

It’s genetic – the debilitating form of premenstrual syndrome with very severe cramps, irritability, breast soreness and muscle aches known as premenstrual dysmorphic disorder has been linked to a group of genes that respond differently to sex hormones.

Between 2 and 5% of women are diagnosed with premenstrual dysphoric disorder (PMDD), which is a particularly severe form of the much more common premenstrual syndrome (PMS).

Researchers have now found that PMDD is caused by a group of genes that affects how sex hormones interact with other genes….

“This is a big moment for women’s health, because it establishes that women with PMDD have an intrinsic difference in their molecular apparatus for response to sex hormones – not just emotional behaviors they should be able to voluntarily control,” said study author David Goldman, a researcher at the US’s National Institutes of Health.

The finding is a significant one for women who suffer from PMDD. There has been relatively little research into PMDD or the more common condition PMS…But this finding may pave the way for better targeted treatments for the condition, which is so disruptive to women’s lives that it drives 15 per cent of PMDD sufferers to attempt suicide.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: ‘A big moment for women’s health’ – genetic basis found for premenstrual mood disorder

The GLP aggregated and excerpted this article to reflect the diversity of news, opinion, and analysis. Click the link above to read the full, original article.
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