Video: World’s tiniest tape recorder made with CRISPR and built from microbes

worldssmalle
[H]ere’s a use for the bacteria we bet you’ve never considered: Scientists at Columbia University Medical Center have created the world’s smallest tape recorder out of e.coli.

Researchers turned Escherichia coli into little recording devices that can not only record their interactions with the environment but time-stamp the events, too, according to a Columbia University press release. The state-of-the-art recording device is from modified pieces of DNA called plasmids. One plasmid was turned into an audio tape of sorts that would create more copies of itself in response to an external signal, which also activated a separate recording plasmid that would insert itself into the process (like a nosy aunt) and serve as a time stamp to the process.

The results were published recently in Science, and the breakthrough comes courtesy of CRISPR–the gene-splicing Nobel Prize bridesmaid. Per the research, the CRISPR-Cas adaptation system naturally copies snippets of DNA of invading viruses so that the immune system can respond more effectively to future invaders. In a statement, researcher Harris Wang, said the “CRISPR-Cas system is a natural biological memory device.”

The technology is still being developed, so for now, CRISPR recordings probably won’t disrupt the recent resurgence of the cassette tape.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: Researchers use CRISPR to create the world’s tiniest tape recorder

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

Screenshot-PM-24
Viewpoint: The herbicide glyphosate isn’t perfect. Banning it would be far worse.
d-b
Blocked arteries, kidney stones, nausea, constipation, fatigue: Long list of health problems caused by too much vitamin D 
circular-bioeconomy-should-focus-on-sustainable-wellbeing
GLP podcast: What's wrong with 'doomsday' environmentalism? It's false.
Screenshot-2026-04-27-at-12.22.38-PM
Running ‘wild’: Last year, RFK, Jr. was given a green light to ‘reform’ chemical policies. Glyphosate illustrates how Trump now has him on a tight leash, and MAHA is furious
bayer-supremecourt-lt
EPA concludes glyphosate is not carcinogenic. Missouri courts say Monsanto failed to warn it might be. SCOTUS weighs in.
Screenshot 2026-02-25 at 11.20
Why the herbicide glyphosate is key to sustainable agriculture
ChatGPT-Image-Apr-22-2026-11_06_18-AM
Wellness influencer nonsense: No, nicotine does not boost cognition and productivity, but it can damage your health 
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.