Expanded screening recommended for BRCA breast cancer gene. Federal panel stops short of suggesting all women should be tested.

maxresdefault
Image: Associated Press

On [August 20], the US Preventive Services Task Force, a panel of federally appointed independent experts that makes recommendations about preventive care, published updated guidelines for testing people for mutations in the genes BRCA1 and BRCA2, some variants of which are associated with increased risks of breast, ovarian, and some other cancers. The new guidelines, which appear in JAMA, expand the group of women recommended to undergo BRCA1/2 risk assessments, but do not recommend broad screening for mutations in the two genes.

The USPSTF recommends that women who meet the updated screening criteria should be evaluated with a risk assessment tool, which will estimate their odds of having a harmful BRCA1/2 mutation. If the assessments indicate a harmful mutation is likely, then genetic counseling and, possibly, genetic testing could follow.

Related article:  Second opinion? Google AI spots breast cancer more accurately than radiologists, in trial

“Sometimes it makes sense for a woman to only get an assessment and undergo counseling, but not genetic testing,” [Stanford University professor of medicine Douglas] Owens notes.

If tests reveal that a woman has BRCA1/2 mutations that put her at an increased risk for cancer, then potential interventions include more screening for BRCA-associated mutations, medications, and surgeries (such as those to remove breasts, ovaries, or fallopian tubes) that could reduce that risk.

Read full, original post: New Guidelines Expand BRCA Screening

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
ft covidresponseus feature

Video: Viewpoint: The US wrote the global playbook on the coronavirus and then ignored it

A year ago, the United States was regarded as the country best prepared for a pandemic. Our government had spent ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
gmo corn field x

Do GMO Bt (insect-resistant) crops pose a threat to human health or the environment?

Bt is a bacterium found organically in the soil. It is extremely effective in repelling or killing target insects but ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend