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Facing Ebola outbreak, Uganda approves 3 experimental treatments

Catherine Offord | 
Health authorities in Uganda have approved the use of three experimental treatments against Ebola in the country. The decision comes ...
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Are we fighting diseases wrong? Researcher suggests a better approach is building tolerance to infection

Ashley Yeager | 
[Researcher Janelle] Ayres was running the experiment to determine what causes genetically identical mice to respond differently to the same ...
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Infographic: These supercomputers mimic human brains to boost computing power

Sandeep Ravindran | 
Neuromorphic hardware takes a page from the architecture of animal nervous systems, relaying signals via spiking that is akin to ...

Video: See how the brain makes memories

Nicholas Turk-Browne | 
Watch Princeton University’s Nicholas Turk-Browne describe his research on how the human brain makes, stores and adjusts memories. Read full, ...
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Stem cell treatment could create ‘living drug’ against cancer tumors

Chia-Yi Hou | 
In a first-of-its-kind clinical trial, a natural killer cell immunotherapy derived from induced pluripotent stem cells is being tested for ...
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Defining life: Why we need to identify the boundary between living things and AI robots

John Loike, Robert Pollack | 
They’re advancing artificial intelligence (AI) to create next-gen personalized robots that can read human emotions in real time. What will ...
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‘Reverse engineering’ our brains with silicon chips could help us understand consciousness

Sandeep Ravindran | 
The fact that computers “think” very differently than our brains do actually gives them an advantage when it comes to ...
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Building artificial brains to help us understand our own

Bob Grant | 
You’d think that overseeing an entire issue of The Scientist focused on artificial intelligence would cause my mind to wander far into ...

Off-target RNA mutations: Why this ‘more precise genome-editing’ technique needs improvement

Catherine Offord | 
Base editors designed to convert one DNA nucleotide to another may also perform large numbers of unwanted edits to RNA, ...
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Cancer has a male bias and we’re just starting to understand why

Jef Akst | 
More than half of neurooncologist Josh Rubin’s pediatric brain cancer patients over his 25-year career have been boys. … About a ...
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Monitoring biodiversity: Project seeks to catalog arctic life through ‘DNA Barcoding’

Phil Jaekl | 
[Molecular biologist Inger Greye] Alsos is currently taking part in the formidable task of genetically identifying not just all the ...
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When cancer becomes contagious: Seeking better understanding of rare transmissible forms of the disease

Katarina Zimmer | 
The untrained eye likely wouldn’t have noticed, but doctoral student Ruth Pye immediately spotted something unusual about the way the cells were ...

Can CAR-T cell therapy tackle solid tumors too?

Kerry Grens | 
Last summer, [Cecelia] Barron’s cancer went from stage 2 to stage 3 oligodendroglioma. Behnam Badie, her surgeon at City of Hope, ...
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CRISPR’s challenge: It’s still easier to subtract genes than it is to add them

Anna Nowogrodzki | 
Almost always, building something is harder than tearing it down. Similarly, knocking in genes poses a greater challenge than knocking ...
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How modern farming may be distorting our analysis of ancient human migration

Anna Azvolinsky | 
One of the most widely used tools archaeologists have at their disposal to decipher where prehistoric humans lived and traveled ...
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Searching for tuberculosis ‘super-spreaders’ by sampling breathed air

Linda Nordling | 
In Masiphumelele, an informal settlement of tin shacks, squat brick buildings, and narrow lanes south of Cape Town, 23,000 people ...
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Japan wants to use stem cells to treat paralysis—but ethical questions remain

John Loike | 
On February 18, 2019, The Asahi Shimbun reported, “Ministry [of Health, Labor and Welfare in Japan] OKs 1st iPS [induced pluripotent ...
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Growing malaria drug resistance worldwide threatens to be ‘disastrous’

Natalie Slivinski | 
It’s not clear why, but the Greater Mekong Subregion—Cambodia, southern China, Laos, Myanmar, Thailand, and Vietnam—is a major source of ...
Calyxt gene-edited soybean oil debuts in Midwestern US restaurants

Calyxt gene-edited soybean oil debuts in Midwestern US restaurants

Carolyn Wilke | 
At the end of [February 2019], Calyxt, an agriculture-focused company based in Minneapolis-St. Paul, Minnesota, announced its first sale of ...

Can the flu cause Parkinson’s and other brain disorders?

Ashley Yeager | 
One of the earliest links between influenza and neural dysfunction was a correlation between the 1918 Spanish flu, caused by ...
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Viewpoint: Creation of synthetic DNA demands ethical boundaries for its use

John Loike, Robert Pollack | 
A study published [February 21] expands the redesign of the 4-billion-year-old genetic code from a four-nucleotide base-pair alphabet to an eight-base-pair ...
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Popular autism ‘signaling imbalance theory’ challenged, suggesting new drugs ‘may have little value’

Sarah Deweerdt | 
An analysis of four mouse models negates certain assumptions underlying the “signaling imbalance theory,” a popular hypothesis about autism’s origins ...
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Keen sense of smell? You’re probably good at not getting lost, study suggests

Shawna Williams | 
Watch a bacterium chase down the source of an enticing molecular trail using chemo-taxis, and it’s clear that its sensory ...
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First gene-editing experiments on adults suffering from rare metabolic disorders offer promising early results

Carolyn Wilke | 
In late 2017, scientists first began attempting to edit the genes of adults to treat rare genetic disorders. Preliminary results ...
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Plant scientists: Anti-GMO activism has warped the public’s understanding of biotechnology

Bryan Delaney, Nicholas Storer, Rod Herman | 
Public perception  of genetically engineered (GE) crops is being manipulated by organizations that purport to represent the interests of consumers ...
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Tracking Neanderthal DNA in modern humans: There’s been little change in 45,000 years

Diana Kwon | 
Neanderthals, modern humans’ closest evolutionary relatives, have been extinct for thousands of years. But due to interbreeding between the two ...
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Infographic: How do urban environments drive genetic change?

Catherine Offord | 
Air pollution may favor the adaptation of organisms to become more stress-resistant than their rural counterparts. There is some evidence ...

Immunotherapy more effective in patients with more cancer mutations, study shows

Catherine Offord | 
The number of mutations in a tumor’s genome may predict how well a patient will benefit from treatment with immune ...