Artificial lungs grown in ‘hijacked’ mouse embryo could pave way for human transplants

d f d d d e f e
Image: Yahoo

Vaping aside, as dangerous air quality becomes increasingly prevalent in cities around the globe, the risk of serious lung disease will only rise.

The problem? Healthy donor lungs are few and far between, and because of their extraordinarily intricate structure, lungs are extremely difficult to perfectly 3D print or otherwise bioengineer.

[November 7], scientists from Columbia University Irving Medical Center, Stanford University, and the University of Tokyo teamed up in an outside-the-box attempt at making lab-grown lungs. Rather than engineering the organ, they hijacked a developing mouse embryo’s innate ability to develop any organ to “grow” third-party lungs right inside the embryo.

In two types of embryos deprived of cells that normally turn into lungs, the team inserted donor stem cells. Under the direction of genetic and chemical signals that orchestrate the entire blueprint of the body, the transplanted cells turned into fully functional lungs that kept the otherwise lung-less host mice alive well past birth.

Related article:  Disease is the greatest threat to bee health. Can we protect them through genetically engineered probiotics?

“Our study shows that it may eventually be possible to develop new strategies for generating human lungs in animals for transplantation as an alternative to waiting for donor lungs,” said Dr. Wellington Cardoso, one of the lead authors of the study.

Read full, original post: How Scientists Grew Perfect New Lungs in Mouse Embryos

Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend