Podcast: How old is your dog in human years? Genetic study offers a new way to answer that question

Print Friendly, PDF & Email
petmd dog age
Image: Pet MD

How old is your four-legged best friend? Common wisdom says that a dog ages seven years for every human year. But Tina Wang, a graduate student at the University of California, San Diego, wanted a more accurate assessment. Her quest started five years ago, when she rescued a dog from a shelter.

Wang worked in Trey Ideker’s lab, where they study changing patterns of DNA methylation in humans. Small chemical entities called methyl groups attach to stretches of DNA, which affects what sequences are active. As we age, some stretches of DNA get more methylated, and others less. The pattern is so consistent over the course of most people’s lives that it can be used as an aging “clock.” The same process happens in dogs—and published reports existed from other labs about methylation patterns in dogs changing over time.

Related article:  Viewpoint: Trump’s inflammatory appeals triggered support for him in 2016. Here’s why scientists think it won’t happen again

So Wang compared the age-related patterns in 320 humans and 104 Labrador retrievers.

The researchers say that dog years per human year change over the lifetime of a dog. For example, their method has a one-year-old dog being the equivalent of a 30-year-old human. A four-year-old dog is about 52. And dog aging per year slows considerably after that.

Read full, original post: Fido’s Human Age Gets New Estimates

Outbreak Featured
Infographic: Autoimmune diseases — 76 identified so far — tend to target women over men. Here is a master list

Infographic: Autoimmune diseases — 76 identified so far — tend to target women over men. Here is a master list

There are many autoimmune diseases, and taken together they affect as much as 4.5 percent of the world’s population. This ...
Are GMOs and pesticides threatening bees?

Are GMOs and pesticides threatening bees?

First introduced in 1995, neonicotinoids ...
glp menu logo outlined

Newsletter Subscription

* indicates required
Email Lists
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.