All CRISPR crops are GMOs in Europe? Groundbreaking court ruling may have been misinterpreted

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Credit: Freepik
Credit: Freepik

In the ruling of July 2018, the Court of Justice of the European Union (CJEU) confirmed that organisms obtained by newer methods of directed mutagenesis such as genome editing are not excluded from the scope of the EU GMO directive.

Following the ruling many in the scientific community assumed that it meant that all genome edited organisms are to be treated as GMOs under the GMO Directive. But this new article, published [January 6] in the European Journal of Risk Regulation, challenges this prescriptive interpretation.

A key factor in interpreting the ruling, the authors argue, has been determining whether organisms fall under the GMO definition in the first place …. The EU definition of a GMO is where: ‘the genetic material of the resulting organisms has been altered in a way that does not occur naturally.’

Related article:  How Brexit will impact the future of farming, GMOs and gene editing in Britain and Europe
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Providing an in-depth analysis, the authors conclude that for an organism to be a GMO in the sense of the directive, the technique used as well as the genetic alterations of the resulting organism must be considered. In short, not every mutation results in a GMO.

Modern gene editing techniques such as CRISPR can be used to give different types of changes, from single base pair changes and deletions, which can occur naturally, to additions and more complex changes which would not. The former therefore is not a GMO as the EU defines it.

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