Drawing a line: European Convention upholds ban on heritable human genome editing

ban on gene-editing of heritable genomes
Credit: Genetic Engineering and Biotechnology News

The Council of Europeโ€™s Convention on Human Rights and Biomedicine, better known as theย Ovideo Convention, explicitly bans heritable human genome editing in the 29 countries that have signed and ratified it. It has done so for close to a quarter century, which is an inconvenient reality for advocates of the technology, who like toย ignoreย orย downplayย theย existenceย of the ban. Failing that, theyย implyย that the Conventionโ€™s prohibition of heritable genetic modification is out of date. It is not. Thatโ€™s the conclusion of a long and detailedย re-examination of the relevant text.

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Acceptable interventionsย include somatic gene therapy (to control or cure a patientโ€™s disease) and related research, which may include โ€œinterventions seeking to modify the human genome for the acquisition of knowledge relevant to these permitted purposesโ€ but emphatically not โ€œto introduce a modification in the genome of any descendants.โ€ In case anyone should try to misunderstand, this โ€œhas the implication that gametes, embryos or their precursors that have been subjected to such intervention may not be used for the purposes of procreation.โ€

All clear now?

A new explanatoryย videoย is also online, featuring Anne Forus, Chair, and Pete Mills, member, of the CDBIO Drafting group on genome editing.

This is an excerpt. Read the full article here

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