Nearly two decades ago, several pharmacists started calling into the University of Florida Drug Information and Pharmacy Resource Center hotline with the same query: Does phenylephrine, a common ingredient in cold medicine sold over the counter, actually work?
Recently, an advisory committee for the F.D.A. unanimously confirmed our findings. The agency must now decide whether products containing the ingredient should be removed from shelves and drug makers should use new formulations.
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This decongestant is like many drugs on the market that don’t really provide relief.
Just ask your local pharmacist about over-the-counter drugs he or she suspects don’t work. It’s an open secret among many of us who study pharmaceuticals that several ingredients, including ones found in common treatments like Robitussin, Mucinex and certain cough syrups, probably don’t work as advertised.