Despite no evidence of health harm in humans, companies scramble to phase out synthetic dyes

On January 15, 2025, the U.S. Food and Drug Administration revoked authorization of Red No. 3 in food, causing it to be phased out by the end of 2027. The agency pointed to a study that found, in high doses, Red No. 3 causes cancer in male rats. This invoked the Delaney Clause, prohibiting authorization by the FDA of a food or color additive if it has been found to induce cancer in humans or animals.

This happened despite the study noting that the mechanism that caused the cancer that is not present in humans and the levels of dosage were not relevant to the levels used in human food human consumption.

As the artificial-dye deadline approaches, companies are making announcements on whether they will be able to make or miss it. Although the push comes from the government, consumers are watching what the industry will do.

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