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Wanted: Volunteers willing to risk getting sick from the coronavirus for the greater good

Carolyn Johnson | 
The Covid-19 Prevention Network, which knits together the existing federal clinical trial infrastructure developed largely to test HIV vaccines and ...
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‘Impenetrable medical jargon’: Why retooling ClinicalTrials.gov should be a priority

Alison Bateman-House, Jamie Webb | 
Millions of people visit ClinicalTrials.gov each year to find a trial that they or a loved one might be eligible ...
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23andMe venturing into business of recruiting patients for clinical trials

Rebecca Robbins | 
Consumer genetics giant 23andMe announced [September 26] that it would move deeper into the business of clinical trial recruitment, partnering with a ...
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‘Permanent fix’ for melanoma, blindness, sickle cell? CRISPR gene editing tackles diseases

Lila Thulin | 
In the past 12 months, four clinical trials launched in the United States to use CRISPR to treat and potentially cure patients ...
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Viewpoint: There’s a problem with autism studies. They rarely use the same set of tools to measure results.

Jyoti Madhusoodanan | 
Clinical trials of autism treatments rarely use a consistent set of tools to measure efficacy, a new study suggests. Instead, ...
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A third of cancer drug clinical trials don’t report on race. Here’s why that matters

Megan Thielking | 
One-third of the clinical trials that led to new cancer drugs approved between 2008 and 2018 didn’t report on the ...
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CRISPR ‘put to the test’ against inherited blindness, blood disease. Next up Duchenne muscular dystrophy, cystic fibrosis

Tina Saey | 
Since its debut in 2012, CRISPR gene editing has held the promise of curing most of the over 6,000 known ...
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CRISPR moves from the lab to human trials, targeting blindness, beta thalassemia and sickle cell anemia

Alice Park | 
It’s only been seven years since scientists first learned how to precisely and reliably splice the human genome using a ...
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What’s next from stem cell research? Diabetes treatments and safer kidney transplants

Kathleen Doheny | 
Treatments for eye diseases are considered among the most promising for stem cells, which have been under study for more ...
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FDA mulling whether patients should have to pay to join clinical trials

Rebecca Robbins | 
Some [clinical trials] plan to ask participants to pay $7,000 or so to enroll. Another wanted to ask for upward ...
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Priming the body’s immune system with personalized cancer vaccines

Elaine Mardis, Jasreet Hundal | 
In 2014, at Washington University School of Medicine in St. Louis, six melanoma patients received infusions of an anticancer vaccine ...
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First attempt at using CRISPR to edit genes inside the body targets inherited form of blindness

Marilynn Marchione | 
Patients are about to be enrolled in the first study to test a gene-editing technique known as CRISPR inside the ...
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‘Found in Translation’: Computer models could help us understand which mice studies matter for human medicine

Kimberly McCoy | 
Machine learning technology could help researchers determine what mouse data are useful when designing human clinical trials ...
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After another promising Alzheimer’s drug trial fails, we have to ask: Are we on the right path to a cure?

Vicky Jones | 
As trial after trial of beta-amyloid drugs fail, there's a possibility that Alzheimer's researchers have the wrong target ...
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Improving personalized medicine may demand more diversity in clinical trials

Edward Abrahams, Jane Delgado | 
Hispanic Americans have higher levels of diabetes and less access to health care services, yet they live on average about ...
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Viewpoint: Study participants should have the right to their own results

Julia Brody | 
Study participants nearly always want their own results. But few get them. … The ethical concern with giving an individual ...
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Large drug trials are expensive and results often misleading. A new genetic tool might cure those problems.

Gary Taubes | 
[C]orrelation is not causation. The fact that two phenomena or trends are correlated in time does not mean one causes ...
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Here’s what happened when a promising clinical trial for depression was halted

David Dobbs | 
Many clinical trials never actually go to completion, however the preliminary results may be promising. What can we get out ...
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We know the placebo effect is biological. Is it also genetic?

Ben Locwin | 
We know that the placebo effect is in part biological: expectations of receiving a palliative leads to brain changes. Are ...
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