Protecting prion protein keeps stem cells young

COULD we stem the tide of ageing by delaying the deterioration of stem cells? A new compound that appears to do just that could help us find ways to protect our organs from age-related wear and tear, experiments in mice suggest.

As we age, so do our mesenchymal stem cells (MSCs): their numbers in our bone marrow decline, and those that are left lose the ability to differentiate into the distinct cell types – such as bone, cartilage, fat and possibly muscle cells – that help in the healing process.

“We think this ageing of stem cells may be linked to the onset of some age-related disorders, such as osteoporosis,” says Ilaria Bellantuono at the University of Sheffield in the UK.

View the original article here: Protecting prion protein keeps stem cells young – New Scientist

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