Genetics influences depression medication’s efficacy

The following is an excerpt.

Unfortunately, antidepressant drugtherapy does not work for everyone. But new research finds that improved identification of genomic predicators — that is, how a person’s genetic makeup might impact their response to medication — will help future treatment of depression.

The National Institute of Mental Health’s STAR*D study, the largest and longest study ever conducted to evaluate depression treatment, has determined that only one-third of individuals respond to the first medication prescribed for depression, and that another one-third do not have an adequate response despite being treated with several medications.

Thus, identifying predictors of antidepressant response could help to guide the treatment of this disorder.

View the original article here: Genetics Impacts Depression Meds’ Effectiveness

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