Genetically-modified bacteria could help mass produce hookworm drugs

Researchers have produced a protein that kills parasitic intestinal worms, by genetically engineering a bacterium similar to those used in probiotics — raising hopes of more effective and safer therapies for infections that affect up to two billion people worldwide.

The protein, Cry5B, has previously been shown to kill parasitic worms. It is normally produced by Bacillus thuringiensis, a bacterium used as an insecticide and not considered safe for use in people.

Bacteria containing Cry5B could be an ideal drug against human parasites, researchers say, as they can be easily and cheaply produced in large quantities, as well as shipped and stored under adverse conditions.

Read the full, original story here: GM bacteria could help mass produce hookworm drugs

 

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