It’s pretty common knowledge that obesity increases the chance that a woman will develop breast cancer, and how her excess adiposity is distributed on her body can be a clue to her risk.
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[In a new study] investigators examined the association between body size-related characteristics such as body mass index (BMI) and waist-hip ratios (WHR) and breast cancer risk for women with different hormone receptor status. They found that both BMI (as an index of overall obesity) and WHR had a positive association with risk of breast cancer. However, depending on the hormone status, the relationship between size indicators and breast cancer risk varied.There was a significant association between BMI and risk of breast cancer — but only for women whose tumors were ER+/PR+, and for premenopausal women.
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Mechanisms responsible for the differences in the effects of overall and central obesity are not clear, the authors stated. They did note that the type of obesity a woman presents with may provide a clue to the type of treatment that would be appropriate — which could differ with respect to the receptor status and menopausal status of the woman.
[Read the full study]
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