Double mastectomy improves prospects for patients with BRCA1 mutation but not BRCA2, study finds

| | March 28, 2018
d c b a c c c bf
Image credit: Irish News
This article or excerpt is included in the GLP’s daily curated selection of ideologically diverse news, opinion and analysis of biotechnology innovation.

Women with a mutant gene that increases their risk of breast cancer can increase their life expectancy with a radical double mastectomy, however this depends on which mutation they carry, a study has found.

Patients with a mutation in the gene BRCA1 lowered their risk of dying prematurely by pre-emptively removing both breasts, according to Dutch researchers.

However the same study, which followed 2,700 women with mutations increasing their risk of breast cancer, found those with the related gene (BRCA2) did not further reduce their risk of dying of the disease by having both breasts amputated.

”For BRCA1 mutation carriers, bilateral risk-reducing mastectomy not only drastically reduces the risk of developing breast cancer, but, as a consequence, also improves breast cancer-specific survival when compared to surveillance,” said lead researcher Dr Annetee Heemskerk-Gerritsen, from Erasmus University Medical Centre in Rotterdam.

Related article:  Ancient art may have been created by people with autistic traits, study suggests

Emma Pennery, clinical director at Breast Cancer Care, said it was vital women were talked through all the risks and benefits when considering their options, and these findings could guide decision making.

“Discovering you have a faulty BRCA gene can be extremely distressing – on top of worrying about getting cancer, people are faced with the excruciating decision of whether to have a double-mastectomy. This research will help steer many towards a course that is right for them.

Read full, original post: Double mastectomy lowers risk of breast cancer death for some women with mutant gene, study finds

Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
a a b b a f ac a

Video: Death by COVID: The projected grim toll in historical context

The latest statistics, as of July 10, show COVID-19-related deaths in U.S. are just under 1,000 per day nationally, which is ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
types of oak trees

Infographic: Power of evolution? How oak trees came to dominate North American forests

Over the course of some 56 million years, oaks, which all belong to the genus Quercus, evolved from a single undifferentiated ...
biotechnology worker x

Can GMOs rescue threatened plants and crops?

Some scientists and ecologists argue that humans are in the midst of an "extinction crisis" — the sixth wave of ...
food globe x

Are GMOs necessary to feed the world?

Experts estimate that agricultural production needs to roughly double in the coming decades. How can that be achieved? ...
eating gmo corn on the cob x

Are GMOs safe?

In 2015, 15 scientists and activists issued a statement, "No Scientific consensus on GMO safety," in the journal Environmental Sciences ...
Screen Shot at PM

Charles Benbrook: Agricultural economist and consultant for the organic industry and anti-biotechnology advocacy groups

Independent scientists rip Benbrook's co-authored commentary in New England Journal calling for reassessment of dangers of all GMO crops and herbicides ...
Screen Shot at PM

ETC Group: ‘Extreme’ biotechnology critic campaigns against synthetic biology and other forms of ‘extreme genetic engineering’

The ETC Group is an international environmental non-governmental organization (NGO) based in Canada whose stated purpose is to monitor "the impact of emerging technologies and ...
Share via
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend