GAANTRY: USDA develops ‘gene-stacking’ solution to fungal pathogens—but will it actually work?

| | August 17, 2018
Image Credit: Ohio State University Extension
This article or excerpt is included in the GLP’s daily curated selection of ideologically diverse news, opinion and analysis of biotechnology innovation.

If climate change is the new normal, farmers in some regions of the world will have to get used to fighting mold and mildew. For wheat growers in particular, fungal blights are already a big problem …. Fungal pathogens are advancing northwards at about 7 kilometers per year on average, worldwide.

Enter the USDA’s Agricultural Research Service (ARS). On June 14, the ARS published a pilot study on an innovative technology called GAANTRY (Gene Assembly in Agrobacterium by Nucleic acid Transfer using Recombinase technologY) that can insert a “stack” of multiple genes simultaneously into plants.

Roger Thilmony, a research molecular biologist at the ARS, says his team inserted 10 genes into Arabidopsis plants …. The genes were transgenic, making the Arabidopsis seedlings glow fluorescent colors so the researchers would know at a glance if the genes had been successfully inserted. However, genes from the same or related species that have some benefit, such as disease resistance, can also be swapped in ….

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Sarah Gurr, a plant pathologist at the University of Exeter, is skeptical about whether GAANTRY is ready for prime time. “Arabidopsis is a little weed and it’s not a crop plant,” she says. “While it’s all fantastic stuff, it isn’t necessarily transferrable from a Brassica, which is what Arabidopsis is, into wheat, which is hugely complex genome-wise.”

Read full, original article: USDA Unveils New Gene-Stacking Tool to Prevent Plant Diseases

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