Podcast: Don’t treat that fever—Dr. Paul Offit on why many of medicine’s most popular practices are ‘overkill’

screenshot breaking a fever treatment and causes
Vaccine skeptics, alternative health advocates and anti-GMO activists are regularly lambasted for ignoring evidence that challenges their ideology. As it turns out, they’re not the only ones who refuse to change their minds when confronted with new data: modern medicine is often guilty of the same intellectual sin, pediatrician and vaccine expert Dr. Paul Offit writes in his new book Overkill: When Modern Medicines Goes too Far.

Never afraid of controversy, Offit argues that many standard practices in modern medicine, for example treating a fever when you’re sick, are at best unhelpful and at worst actually dangerous. Enduring a fever is of course a miserable experience, but it helps our immune system fight off deadly bacterial and viral infections. Blocking this important immune response with antipyretics (aspirin, acetaminophen, ibuprofen) may lead to 40,000 additional flu-related deaths every year.

x
Credit: HarperCollins

A similarly contrarian case can be made for antibiotics. While clearly necessary to kill harmful bacteria, the research shows that patients often don’t need to finish an antibiotic course, and doing so encourages the spread of drug-resistant bugs and brings us closer to losing antibiotics for good. Many doctors nonetheless continue prescribing them for far longer than necessary to treat their patients.

But that’s just the beginning, Offit claims. From heart stents and surgery for knee arthritis to prostate cancer exams, research has shown that these practices are pointless or more harmful than helpful—yet physicians and patients refuse to adjust to the evidence.

On this episode of Science Facts and Fallacies, Offit joins GLP editor Cameron English to explain why and how modern medicine continues to promote fifteen common medical interventions that “have long been considered gospel despite mounting evidence of their adverse effects.” Offit also gives his take on the coronavirus pandemic, the possibility of developing an effective immunization and how the anti-vaccine movement might react to the COVID-19 crisis.

Paul Offit is a pediatrician specializing in infectious diseases and the co-inventor of the rotavirus vaccine RotaTeq. Visit his website and follow him on Twitter @DrPaulOffit

Cameron J. English is the GLP’s senior agricultural genetics and special projects editor. He is a science writer and podcast host. BIO. Follow him on Twitter @camjenglish

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Sep-2-2026-02_03_32-PM
How much of a problem is AI’s water use?
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
ChatGPT-Image-Sep-10-2026-01_44_53-PM
Viewpoint: Why medical and health nonsense spreads so casually on pop culture media
Screenshot-2026-09-16-at-3.14.20-PM
19%: Plunging support for Trump-RFK, Jr. measles vaccine safety oversight
ChatGPT-Image-Sep-17-2026-12_28_43-PM
Vitamin D, omega-3 fish oil and glucosamine supplements could cause brain damage 
Screenshot-2026-09-16-at-2.26.42-PM
Viewpoint: How to ecologically damage America’s forests: Ban glyphosate
ChatGPT-Image-Sep-16-2026-11_28_54-AM
Viewpoint: Study links childhood vaccination to autism!!! Here’s how anti-vaxxers twist evidence to corrupt science
ChatGPT-Image-Sep-21-2026-10_55_04-AM
Viewpoint: America’s food-safety system is being methodically dismantled by the Trump administration.
ChatGPT-Image-Sep-17-2026-11_03_54-AM-2
AI sparks a bioweapons race
ChatGPT-Image-Sep-21-2026-02_35_25-PM
22-year frozen embryo: In one of the longest delayed births ever, middle-aged Greek couple gives birth to a daughter
ChatGPT-Image-Sep-21-2026-10_18_59-AM-2
Viewpoint: Is corporate embrace of regenerative agriculture greenwashing?
Screenshot-2026-09-18-at-2.28.16-PM
Is the Defense Department gobbling up research dollars originally targeted for medical research?
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.