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“By looking at the overall profile of the immune response, we can begin to truly understand how the immune system responds to COVID-19 and then use that knowledge to prevent the worst outcomes of this disease,” [said researcher Galit Alter.]
It’s still not clear why some individuals infected with SARS-CoV-2 recover from infection and others die, the authors noted. “While the rapid spread of SARS-CoV-2, even during the asymptomatic phase of this infection, is alarming, more harrowing is our inability to predict disease trajectories among symptomatic individuals.” And without any therapeutics or vaccines as countermeasures, there is “an urgent need” to start mapping how immunity to the virus starts to develop. This knowledge will not only help to guide patient care, but could help to direct the development of future immune-based strategies against the disorder.