While there’s growing evidence that psychedelic drugs can effectively treat severe mental health conditions, especially in cases where traditional treatments have failed, they still come with downsides.
Their hallucinogenic effects can be scary and overwhelming, with dosing sessions lasting several hours.
Mindstate Design Labs is one of a slate of new companies aiming to make safer psychedelics by removing the classic “trip” associated with them. The company is using AI to help design psychedelic-like drugs that induce specific mental states without hallucinations, and its first compound looks promising.
While participants reported heightened emotions, associative thinking, enhanced imagination, and perceptual effects such as colors looking brighter, they did not experience hallucinations, self-disintegration, oceanic boundlessness and other typical features of a psychedelic trip.
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Psychedelics work on the brain’s serotonin system by promoting neuroplasticity, which involves the growth of neurons and the formation of new connections. Some researchers believe that this ability to stimulate neuroplasticity, rather than the hallucinogenic effects, is the key to treating mental illness.
