Is cellular reprogramming junk science? Nearly 20 patients are getting eye injections in the first FDA-cleared cellular trial

It’s a pivotal moment for longevity science, the first opportunity for researchers to prove that epigenetic reprogramming — a technique that trains aging cells to act young again — can actually improve how people age in the real world.

On Tuesday, Boston-based biotech startup Life Biosciences announced that its first patient has been dosed with a cellular reprogramming injection, designed to reverse age-related diseases.

…

In this case, the injection went into one eyeball of a single person with glaucoma. … Over the next six months, scientists will be watching to see how well the technique works, while doctors keep an eye out for any safety issues.

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The company’s cofounder, Harvard geneticist David Sinclair, is one of the most well-known and controversial figures in longevity science. Sinclair, who’s no longer involved in the day-to-day operations at Life Biosciences, has been known for hyping up his own experimental anti-aging treatments that have never quite met expectations. But for all his misses, his ideas helped lay the foundation for this new trial, which, if successful, could be groundbreaking.

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