Orange ‘super banana’: Gates-funded Ugandan scientists develop vitamin A enhanced fruit that could help reduce blindness and save lives

PVA-biofortified “Cavendish” banana in Australia. Credit: Jean-Yves Paul via CC-BY-4.0
PVA-biofortified “Cavendish” banana in Australia. Credit: Jean-Yves Paul via CC-BY-4.0

Wilberforce Tushemereirwe holds up a genetically modified banana that took millions of dollars and 20 years to make. It contains so much provitamin A, a substance that transforms into vitamin A in the body, that its flesh has a distinctive orange tint.

This “super banana” was created at Uganda’s National Agricultural Research Laboratories (NARL) for the noblest of causes: to save the lives of thousands of children who die in Uganda every year from vitamin A deficiency. Scientists have long crossbred banana plants to improve resistance to pests, fungus, or drought. But fortifying bananas to deliver nutrients to humans who eat them is a first.

The breakthrough is the result of a partnership of the lab in Kawanda, where Tushemereirwe serves as director, James Dale, an Australian agricultural scientist and banana expert, and the Bill and Melinda Gates Foundation, which invested $11 million in one of the longest running research projects the foundation has ever undertaken.

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The Ugandan government has tried for decades to solve the problem—with limited success. Distribution of vitamin A capsules, for example, worked well in urban areas but failed to reach those most in need in rural areas. Fortifying maize and wheat flour and edible oils with vitamin A to boost nutritional values proved more effective. But those foods are not consumed in large enough amounts to make a meaningful difference.

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