Weight loss and fertility: Ozempic users report unexpected side effect — surprise pregnancies

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Credit: Good Morning America

Across social media, women who have used Ozempic or similar medications for diabetes or weight loss are reporting an unexpected side effect — surprise pregnancies.

The Facebook group “I got pregnant on Ozempic,” has more than 500 members. Numerous posts on Reddit and TikTok discuss unplanned pregnancies while on Ozempic and similar drugs which can spur significant weight loss by curbing appetite and slowing the digestive process. The drugs are known as “Glucagon-like peptide 1” or GLP-1 drugs.

The reports of an Ozempic baby boom are anecdotal, and it’s not known how widespread the phenomenon is. Experts say significant weight loss can affect fertility. Others speculate that the GLP-1 drugs could interfere with the absorption of oral contraceptives, causing birth control failures.

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The drugs also may interfere with oral contraceptives in some patients, doctors say. The GLP-1 drugs help people lose weight by slowing gastric emptying, curbing hunger and leaving people feel full sooner. It may be that the GLP-1 drugs also affect the absorption of oral contraceptives, said William Dietz, physician and chair of the STOP Obesity Alliance at the Milken Institute School of Public Health at George Washington University. “This may mean that birth control medications are metabolized or ineffective,” he said.

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