One shot to lower risk of heart attacks? Early-stage CRISPR therapy safely cut “bad” cholesterol and triglycerides by more than 50% patients

One shot to lower risk of heart attacks? Early-stage CRISPR therapy safely cut “bad” cholesterol and triglycerides by more than 50% patients

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in ...
DNA pioneer James Watson’s remarkable—and controversial—career

DNA pioneer James Watson’s remarkable—and controversial—career

Malcolm Ritter |
Discovering the structure of ... DNA was a breakthrough that would help open the way to a revolution in medicine, ...
Viewpoint: No, we should not follow RFK, Jr.’s recommendation and quickly phase out biomedical research animal testing 

Viewpoint: No, we should not follow RFK, Jr.’s recommendation and quickly phase out biomedical research animal testing 

Anis Barmada |
In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal ...
The genetics of food cravings and aversions

The genetics of food cravings and aversions

Lauren Jean Lobsinger |
The binding interaction between taste receptors and food compounds drives our sensory preferences. Researchers are paving the way for personalized ...
Why Texas and its marginalized communities are the epicenter of MAHA’s food and health movement

Why Texas and its marginalized communities are the epicenter of MAHA’s food and health movement

Isabella Cueto |
With its diverse population, a political establishment eager to please the Trump administration, and a cabal of prominent MAHA converts, ...
‘The science is almost non-existent’: Latest longevity fad: N.A.D. supplements. Here’s an explainer

‘The science is almost non-existent’: Latest longevity fad: N.A.D. supplements. Here’s an explainer

Mohana Ravindranath |
Nicotinamide adenine dinucleotide, or N.A.D.+, is a molecule found in all cells that’s essential for repairing damage, generating energy and ...
The public health establishment takes on the insurrectionist MAHA movement and searches for common ground

The public health establishment takes on the insurrectionist MAHA movement and searches for common ground

Pien Huang |
Dr. Georges Benjamin has seen many infectious disease outbreaks and bioterrorism threats in the near-25 years he's led the American ...
What happens when weight loss drug users phase out too fast?

What happens when weight loss drug users phase out too fast?

Holli Bradish-Lane |
We celebrate the success stories of GLP-1s, but we rarely talk about the crash that follows when treatment stops. And ...
Viewpoint: Beware the cancer quacks: Here’s why ‘functional-medicine-doctor-practicing-without-a-license’ Casey Means is a disaster choice for surgeon general

Viewpoint: Beware the cancer quacks: Here’s why ‘functional-medicine-doctor-practicing-without-a-license’ Casey Means is a disaster choice for surgeon general

Steven Salzberg |
It appears that our next U.S. Surgeon General will be Casey Means, who labels herself a “functional medicine” doctor. Or ...
Viewpoint: A 33%+ drop in food allergies challenges RFk, Jr.’s scientifically unsupported claim that aluminum in vaccines is causing a surge

Viewpoint: A 33%+ drop in food allergies challenges RFk, Jr.’s scientifically unsupported claim that aluminum in vaccines is causing a surge

Kiera Butler |
[A] new study published in the journal Pediatrics found the rate of food allergies has declined from about 1.5 percent of all American children ...
GLP podcast: Obesity—Disease or Choice? Ozempic’s Triumph Reignites the Debate

GLP podcast: Obesity—Disease or Choice? Ozempic’s Triumph Reignites the Debate

Cameron English |
US obesity rates are falling from a record high after steadily climbing since the 1960s, dropping to 37 percent this ...
Miracle mineral? Magnesium is the hottest-selling supplement. Does it work? Can it be dangerous?

Miracle mineral? Magnesium is the hottest-selling supplement. Does it work? Can it be dangerous?

Ruth Clegg |
In the fast-moving world of supplements, it's magnesium's time to shine. And the industry is booming. The global magnesium market ...
brain

Curing Alzheimer’s: Unwinding mystery of the 76-year-old man with a disease that (until now) always caused dementia by 50 

Pam Belluck |
Mr. Whitney, 76, is a scientific unicorn with potential to provide answers about one of the world’s most devastating diseases ...
Ultra-processed foods stimulate dopamine and are addictive? Latest science challenges activist consensus

Ultra-processed foods stimulate dopamine and are addictive? Latest science challenges activist consensus

Vladimir Hedrih |
A neuroimaging study of young, healthy adults showed that consuming a milkshake did not, on average, result in a significant ...
Viewpoint: The science behind seasonal affective disorder

Viewpoint: The science behind seasonal affective disorder

Linda Geddes |
Although seasonal affective disorder (Sad) was only formally recognised by psychiatrists in the 1980s, the link between the seasons, mood ...
Should women heed RFK, Jr.'s warning that COVID shots can harm children of pregnant women? New study says 'no'

Should women heed RFK, Jr.’s warning that COVID shots can harm children of pregnant women? New study says ‘no’

Mary Van Beusekom |
A new study suggests that children of mothers who had COVID-19 during pregnancy are at 29% higher risk of neurodevelopmental ...
Peanut allergies have plunged 43% in 8 years. Here’s how it was accomplished

Peanut allergies have plunged 43% in 8 years. Here’s how it was accomplished

Bryan Walsh |
Researchers at Children’s Hospital of Philadelphia (CHOP) compared peanut and food allergies before pediatric guidelines about feeding changed in 2017 and after, ...
Is Vitamin D the anti-aging pill we’ve been looking for?

Is Vitamin D the anti-aging pill we’ve been looking for?

Dervla Kelly |
Vitamin D supplements could help protect the caps on our chromosomes that slow ageing, sparking hopes the sunshine vitamin might ...
The resurrection of the dire wolf is phony, but Colossal Biosciences' de-extinction research could revolutionize drug development and healthcare

The resurrection of the dire wolf is phony, but Colossal Biosciences’ de-extinction research could revolutionize drug development and healthcare

Meagan Parrish |
Similar to the way NASA’s effort to launch humans into space once triggered a frenzy of technological advances in areas ...
California takes on the thorny challenge to define what constitutes a nutritious lunch for school children. How is it doing?

California takes on the thorny challenge to define what constitutes a nutritious lunch for school children. How is it doing?

Charles Dinerstein |
California has once again stepped to the front of the regulatory line—this time in the school cafeteria. While Washington dithers ...
Viewpoint: RFK, Jr. and vaccines — here’s what a prominent physician says he gets dangerously wrong

Viewpoint: RFK, Jr. and vaccines — here’s what a prominent physician says he gets dangerously wrong

Jake Scott |
In the months since he began serving as secretary of the Department of Health and Human Services, Robert F. Kennedy ...
Treating Huntington’s

Treating Huntington’s

Henry Miller |
During my neurology rotation as a medical student, one of my first patients was in the middle stage of much-dreaded ...
Preserved poop offers a window into the health and life of ancient humans

Preserved poop offers a window into the health and life of ancient humans

Katherine Courage |
Feces is an open window into the many other organisms living in our bodies—from beneficial bacteria to harmful parasites. The genetic material ...
Viewpoint: Tort lawyer RFK, Jr. — Trump alliance trashing Tylenol opens the door to a flood of dubious lawsuits

Viewpoint: Tort lawyer RFK, Jr. — Trump alliance trashing Tylenol opens the door to a flood of dubious lawsuits

Caitlin Owens |
A lawsuit Texas filed ... against the makers of Tylenol foreshadows a wave of legal warfare enabled by the Trump ...
Viewpoint: Europe’s precautionary principle guiding science regulations is broken. Here’s what needs to be done

Viewpoint: Europe’s precautionary principle guiding science regulations is broken. Here’s what needs to be done

David Zaruk |
Precaution is common sense. We don’t run blindly into a busy street or touch a hot flame. When a toddler ...
image

Happy 43rd birthday, GMO insulin. FDA approval in 1982 took 5 months. How many years would it take now?

Henry Miller |
This is the 43rd anniversary of one of biotechnology’s most significant milestones — the approval by the Food and Drug ...
sleep updated x feature

How much sleep do we really need?

Daryl Austin |
[Sleep] is more than a luxury or idle downtime, it’s a vital biological process that supports nearly every system in ...