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‘Impenetrable medical jargon’: Why retooling ClinicalTrials.gov should be a priority

Millions of people visit ClinicalTrials.gov each year to find a trial that they or a loved one might be eligible ...
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23andMe venturing into business of recruiting patients for clinical trials

Consumer genetics giant 23andMe announced [September 26] that it would move deeper into the business of clinical trial recruitment, partnering with a ...
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‘Permanent fix’ for melanoma, blindness, sickle cell? CRISPR gene editing tackles diseases

In the past 12 months, four clinical trials launched in the United States to use CRISPR to treat and potentially cure patients ...
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Viewpoint: There’s a problem with autism studies. They rarely use the same set of tools to measure results.

Clinical trials of autism treatments rarely use a consistent set of tools to measure efficacy, a new study suggests. Instead, ...
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A third of cancer drug clinical trials don’t report on race. Here’s why that matters

One-third of the clinical trials that led to new cancer drugs approved between 2008 and 2018 didn’t report on the ...
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CRISPR ‘put to the test’ against inherited blindness, blood disease. Next up Duchenne muscular dystrophy, cystic fibrosis

Since its debut in 2012, CRISPR gene editing has held the promise of curing most of the over 6,000 known ...
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CRISPR moves from the lab to human trials, targeting blindness, beta thalassemia and sickle cell anemia

It’s only been seven years since scientists first learned how to precisely and reliably splice the human genome using a ...
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What’s next from stem cell research? Diabetes treatments and safer kidney transplants

Treatments for eye diseases are considered among the most promising for stem cells, which have been under study for more ...
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FDA mulling whether patients should have to pay to join clinical trials

Some [clinical trials] plan to ask participants to pay $7,000 or so to enroll. Another wanted to ask for upward ...
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Priming the body’s immune system with personalized cancer vaccines

In 2014, at Washington University School of Medicine in St. Louis, six melanoma patients received infusions of an anticancer vaccine ...
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First attempt at using CRISPR to edit genes inside the body targets inherited form of blindness

Patients are about to be enrolled in the first study to test a gene-editing technique known as CRISPR inside the ...
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‘Found in Translation’: Computer models could help us understand which mice studies matter for human medicine

Machine learning technology could help researchers determine what mouse data are useful when designing human clinical trials ...
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After another promising Alzheimer’s drug trial fails, we have to ask: Are we on the right path to a cure?

As trial after trial of beta-amyloid drugs fail, there's a possibility that Alzheimer's researchers have the wrong target ...
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Improving personalized medicine may demand more diversity in clinical trials

Hispanic Americans have higher levels of diabetes and less access to health care services, yet they live on average about ...
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Viewpoint: Study participants should have the right to their own results

Study participants nearly always want their own results. But few get them. … The ethical concern with giving an individual ...
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Large drug trials are expensive and results often misleading. A new genetic tool might cure those problems.

[C]orrelation is not causation. The fact that two phenomena or trends are correlated in time does not mean one causes ...
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Here’s what happened when a promising clinical trial for depression was halted

Many clinical trials never actually go to completion, however the preliminary results may be promising. What can we get out ...
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We know the placebo effect is biological. Is it also genetic?

We know that the placebo effect is in part biological: expectations of receiving a palliative leads to brain changes. Are ...