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Knocking out cholesterol genes could offer ‘one-and-done’ CRISPR cure for heart disease

When CRISPR “base editing” was used to knock out two cholesterol-associated genes in monkeys, the animals’ blood levels of heart-disease-causing ...
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1 year later, first gene edited sickle cell patient is functionally cured

She's the first person with a genetic disorder to get treated in the United States with the revolutionary gene-editing technique ...
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Scanning the horizon for the next decade’s biotech breakthroughs, including tools to fight the next pandemic

In 2017 we published the results of a ‘horizon scan’ that looked at emerging issues in bioengineering (Wintle et al., ...
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Engineering transparent human cells brings us one step closer to a true ‘Invisible Man’

The project involves genetically engineering human cells to have the ability to vary their transparency. This is based on a ...
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Infographic: What CRISPR is curing in 2020

CRISPR-Cas9 is a method for quickly and accurately editing the genome of virtually any living thing. Using custom-built guide RNA ...
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11 things to know about genetic engineering, including how it’s helping us fight disease

What are some interesting facts about genetic engineering, and why it is important? … Genetically engineered things are actually all ...
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Squids’ ability to edit their own RNA could lead to human disease treatments

For nearly every animal on Earth, any changes made to the DNA are transmitted from the cell nucleus by messenger ...
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CRISPR pioneer Jennifer Doudna on why we need human gene-editing regulations

In this episode of Reset, host Arielle Duhaime-Ross talks with Jennifer Doudna about the promise and peril in CRISPR’s future, what’s ...
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Infographic: What the US public thinks about tinkering with human genetics

The Pew Research Center published a fascinating roundup of studies that revealed the opinions of the U.S. public on a ...
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Revamped CRISPR could be more accurate and effective against human diseases, including sickle cell anemia

CRISPR is not perfect. Base editors (think of them as gene-editing pencils) can rewrite individual DNA letters. They home in ...
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Why China scientist’s CRISPR baby scandal won’t be the last ethical ‘grenade’ for human gene editing

Over the next two years, via a series of stakeholder meetings and online consultations, talks with ethicists, academics, patient groups, ...
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‘Excitement is finally catching on’: Why RNA editing may be more promising than CRISPR

CRISPR editing — at least as a therapeutic technique in people — has turned out to be more difficult than ...
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GLP’s Global Gene Editing Regulation Tracker and Index: Will politicians embrace innovation or fear?

We hope this gene editing regulation tracker and index will encourage science-based scrutiny and advocacy ...
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Viewpoint: In the face a gene-editing revolution, President Trump should push for moratorium on human germline editing

In the face of the rapid development of the most powerful technologies ever invented — CRISPR germline gene editing, “artificial ...
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Why it’s so difficult for human embryos to survive CRISPR gene editing

CRISPR may one day wipe out devastating genetic diseases throughout entire family lines, or even the human race. But to ...
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‘Genome doping’: Gene-edited babies could change the world of athletics

With the taboo on human gene editing in the process of being shattered, children whose genomes have been modified before ...
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Genetics pioneer George Church on support for human gene editing: As long as it’s open to everyone—rich or poor

Is it ethical to genetically engineer people? Leading geneticist George Church spends a lot of time thinking about the answer ...
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There’s still a lot we don’t know about China’s controversial CRISPR babies, including their health status

Chinese scientist He Jiankui shocked the world by claiming he had helped make the first gene-edited babies. One year later, ...
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Are we ignoring ‘staggering risks’ of human gene editing, including a wider gap between haves and have nots?

Biologists recently revealed a new form of the gene-editing tool known as Crispr that allows researchers to make precise changes ...
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It’s been a year since the CRISPR baby controversy. Why are we still without global gene-editing rules?

Around this time last November, Chinese scientist He Jiankui stunned the world when he revealed the birth of the first ...
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CRISPR-based cancer therapy passes first test with ‘encouraging’ results

The powerful gene-editing technique known as CRISPR has raised a lot of hope in recent years for its potential to offer new ...
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CRISPR got an upgrade. ‘Prime editing’ offers more accurate ‘search-and-replace’

All right, let’s do this one last time. My name is CRISPR. I was made from a bacterial defense system, and ...
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Viewpoint: Moving forward with human gene editing requires scientists to ‘educate, engage, and empower’ the public, policymakers

Researchers have long struggled to draw a line around ethical genome editing. While modifications to somatic cells only affect a single individual, ...
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Viewpoint: Global moratorium on human gene editing ‘inadvisable’ for 3 reasons, including potential research delays

Heritable genome editing (HGE) of the human germline has potential as a niche assisted reproductive technology. If it can be ...
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Should we use gene editing on human newborns? Exploring scientific arguments for, and against, what may be inevitable

[L]et’s take a closer look at the headline question in own words of scientists. Below are exact quotes from documents, ...
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‘Temporary hurdle’: Russia halts scientist’s effort to create more CRISPR babies

Russian health officials are playing down international concerns that a Moscow researcher plans to create gene-edited babies any time soon, ...
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California man invites scientists to experiment with CRISPR on his rare disorder

On one level, Malakkar Vohryzek always knew what was wrong with him. For as long as he can remember — ...
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Viewpoint: The key to ethical human germline editing is ‘slow science’

The hubris of some scientists knows no bounds. Less than a year after He Jiankui, a Chinese biophysicist, drew scorn ...
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