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Blaming overdiagnosis of cancer on ‘irrational exuberance’: Are we too concerned about early detection?

H. Gilbert Welch |
Even though overall mortality from cancer is falling, the overall incidence is rising. The declines in lung, stomach, cervical, and ...
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Mental health apps are reading your texts—some of them are selling your data, raising privacy concerns

Dana Smith |
An app for monitoring people with bipolar disorder and schizophrenia is so precise it can track when a patient steps ...
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23andMe venturing into business of recruiting patients for clinical trials

Rebecca Robbins |
Consumer genetics giant 23andMe announced [September 26] that it would move deeper into the business of clinical trial recruitment, partnering with a ...
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California man invites scientists to experiment with CRISPR on his rare disorder

Sharon Begley |
On one level, Malakkar Vohryzek always knew what was wrong with him. For as long as he can remember — ...
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This winter’s flu vaccine may not be ‘optimally protective’. We could be in for a rough season.

Helen Branswell |
Twice a year influenza experts meet at the World Health Organization to pore over surveillance data provided by countries around ...
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Viewpoint: The key to ethical human germline editing is ‘slow science’

Françoise Baylis |
The hubris of some scientists knows no bounds. Less than a year after He Jiankui, a Chinese biophysicist, drew scorn ...
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Switching to a new polio vaccine was supposed to be a step forward. Now some experts suggest going back

Helen Branswell |
Three years ago, the leaders of the international campaign to eradicate polio pulled off a landmark feat, phasing out a problematic ...
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AI and digital health devices: FDA’s new guidelines seek to ‘strike a delicate balance’ between safety and innovation

Casey Ross |
The Food and Drug Administration has issued new guidelines on how it will regulate mobile health software and products that ...
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Researcher backtracks on study suggesting He Jiankui’s controversial CRISPR babies will have shorter lifespans

Rebecca Robbins |
A scientific study published this past spring came with damning implications for Chinese scientist He Jiankui, who created the world’s first ...
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Worried about genetic privacy? This start-up is offering anonymous DNA sequencing

Sharon Begley |
The upstart direct-to-consumer DNA-testing company Nebula Genomics announced on [September 19] that it will offer anonymous genome sequencing, becoming the first to do ...
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CRISPR could save the lives of sick children by tweaking the embryos of their siblings

Andrew Joseph |
[Tweaking an embryo’s DNA can] help save someone who is already alive. Take the case of Jessica and Keith, a ...
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HPV vaccines are not just for women: Throat, mouth cancer rates rising for men

Matthew Herper |
Earlier this year, the biotech community mourned the loss of Michael Becker, a former pharmaceutical industry executive. … Becker’s cancer was ...
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Viewpoint: Study’s inability to find a ‘gay gene’ provides affirmation for LGBTQ community

Emily Conley |
As a scientist, I am fascinated by the new international study that found thousands of genetic variants associated with same-sex sexual behavior, ...
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In the age of DNA, sperm donors can no longer expect promises of anonymity to stand up

Meghana Keshavan |
For generations, it was a basic tenet of donating sperm: Clinics could forever protect their clients’ identities. But, increasingly, donor ...
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FDA investigation: Traces of possible carcinogens found in common heartburn meds, including Zantac, raising pharmaceutical supply chain safety concerns

Ed Silverman |
Regulators in the U.S. and Europe are investigating why traces of a possible carcinogen were found in certain heartburn drugs, ...
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Meet biohacker Anastasia Synn, magician with 26 self-implanted microchips and magnets under her skin

Anastasia Synn, Rebecca Robbins |
[Anastasia] Synn has 26 microchips and magnets implanted throughout her body. Unlike many biohackers who experiment purely out of personal ...
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Overreaction? Newly proposed definition of pain could withhold opioids from those who need them most

Dawn Downton |
A new definition of pain is out for comment from the International Association for the Study of Pain, an influential ...
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Viewpoint: Animal rights activists ‘reckless’ and ‘inhumane’ for pushing back against animal testing to find an AIDS vaccine

Matthew Bailey |
In July, researchers eliminated HIV from the genome of a mouse using antiviral therapy and CRISPR-Cas9 gene editing. It was the first ...
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Gates Foundation awards $12 million to teams hunting for universal flu vaccine

Helen Branswell |
Scientific teams from inside and outside the world of influenza research have been awarded funding to try to unlock mysteries ...
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Pregnant women, teenagers warned to stay away from marijuana by surgeon general

Lev Facher |
The federal government on [August 29] issued an advisory warning against marijuana use in teenagers and pregnant women, cautioning that ...
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Menopausal hormone therapy linked to breast cancer risk—even after patients stop taking drugs

Megan Thielking |
A sweeping new analysis adds to the evidence that many women who take hormone therapy during menopause are more likely ...
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‘All of Us’: NIH precision medicine study will share genetic data with participants, offer counseling

Lev Facher |
The nearly 200,000 Americans who have trusted federal scientists with their DNA, their medical records, and detailed behavioral surveys will ...
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We can cure Alzheimer’s, schizophrenia, glioblastoma in mice. Why not humans?

Sharon Begley |
Lab mice endure a lot for science, but there’s often one (temporary) compensation: near-miraculous recovery from diseases that kill people ...
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A third of cancer drug clinical trials don’t report on race. Here’s why that matters

Megan Thielking |
One-third of the clinical trials that led to new cancer drugs approved between 2008 and 2018 didn’t report on the ...
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DNA sequencing clinics catering to curious wealthy clients

Rebecca Robbins |
Seizing on the surging popularity of at-home DNA testing kits, top academic medical institutions are opening clinics that promise to ...
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Viewpoint: Our efforts to learn more about cannabis benefits, risks are hampered by federal research barriers

As cannabis researchers, we work in a field whose unknowns could positively or negatively affect the health of millions of ...
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Viewpoint: FDA should expand drug safety test program to include new technologies, including ‘organs on a chip’

Elizabeth Baker |
Every March, thousands of toxicologists from around the world gather for the Society of Toxicology’s annual meeting. Animal-based approaches once ...