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There was an opioid epidemic 130 years ago. Can it teach us anything about today’s crisis?

Haider Warraich | 
The 1890s and 1990s were both characterized by unopposed amplification of the benefits of opioids, the transformation of physicians into ...
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Viewpoint: 4 ways the FDA must evolve to deal with fast-moving technologies and health threats

Ellen Sigal, Mark McClellan | 
As we look toward the FDA of the 2020s that can achieve further progress in addressing urgent health threats and ...
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Is the quest for profits getting in the way of ending the HIV epidemic?

Four decades after the HIV epidemic began, there’s finally hope it might end. Indeed, “Getting to Zero” — meaning zero ...
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Those childhood vaccinations for tetanus and diphtheria should cover you for life, study says

Elizabeth Cooney | 
People who got all their vaccinations against tetanus and diphtheria in childhood don’t need booster shots to remain protected against ...
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Seeking new momentum in Alzheimer’s research after decades of slow progress

Andrew Joseph | 
5.8 million Americans have Alzheimer’s, with a new person developing the condition about every minute of every day. There is still ...
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‘A real mystery’: Why hasn’t anyone attempted to make a cloned human baby?

Henry Greely | 
For nearly seven years, then, the scientific community has had solid proof that human embryos can be cloned. ...  So ...
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Viewpoint: We still haven’t agreed on the definition of biological aging. That needs to change

Patti Neighmond | 
I’ve been committed to understanding the biology of aging since I was a teenager, and my education and career took ...
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Viewpoint: My daughter taught me that ‘broken’ genes shouldn’t always be fixed

Ethan Weiss | 
Ruthie is a vibrant teenager. She will never learn how to drive and or read normal-sized print without assistive technology, ...
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Viewpoint: ‘Hunches’ can’t be used to decide the fate of ‘covertly conscious’ patients in vegetative states

Adrian Owen, Charles Weijer, Mackenzie Graham | 
[A]s many as 15% to 20% of patients who have been rigorously diagnosed as being in a persistent vegetative state ...
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Unconventional drug ‘lottery’ will hand out 50 doses of Zolgensma, world’s most expensive gene therapy

Andrew Joseph, Ed Silverman | 
The lottery that began [recently] was not about money, or about choosing a school, or about obtaining a visa. It ...
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Viewpoint: We can’t trust research about the benefits of marijuana if the studies are industry funded

Shaun Khoo | 
Imagine that scientists charged with doing research on tobacco’s health implications were funded by tobacco companies. (In fact, the tobacco ...
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If China’s coronavirus isn’t contained soon, we may be stuck with it permanently

Sharon Begley | 
With the new coronavirus spreading from person to person (possibly including from people without symptoms), reaching four continents, and traveling faster than ...
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Viewpoint: AI has one glaring weakness in health care: There’s no human touch

Oliver Drouin, Samuel Freeman | 
It might be that, as physicians who work in a public health care system that relies on fax machines, carbon ...
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Viewpoint: Confronting coronavirus outbreak requires us to cope with our own ‘paralyzing’ fears

Danielle Ofri | 
Fear is a primal emotion, and to pretend that the medical staff are any less susceptible than the general public ...
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Viewpoint: Chronic pain sufferers are needlessly ‘stigmatized’ and how we can change that

Daniel Goldberg | 
Millions of people who live with chronic pain experience intense stigma. I view stigma as the combination of difference plus ...
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‘We’ve only begun to scratch the surface’: How the cannabis boom opens the door to new medicines and wellness products

Andrea Holmes | 
Cannabis, and what it might be able to do for human health, inspires me. And I think it can do ...
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A video game for ADHD? We’re still waiting to see what the FDA thinks

Rebecca Robbins | 
In mid-2018, the startup Akili Interactive Labs asked the Food and Drug Administration to let it do something that’s never ...
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Refining CAR-T therapy could halt ‘violent, life-threatening’ immune reactions

Sharon Begley | 
CAR-T cells that have been so successful against some leukemias and lymphomas often cause a violent and even life-threatening immune ...
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Aging is ‘truly personal’: You could have the immune system of a teenager and the metabolism of a 50-year-old

Sharon Begley | 
One 50-year-old has the nimble metabolism of a teenager, while another’s is so creaky he developed type 2 diabetes — ...
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Psychedelics have ‘extraordinarily potent’ anti-inflammatory power. Is there a place for them in mainstream medicine?

Shlomi Raz | 
Research on psychedelics, which have been profoundly stigmatized, highly restricted, and tragically undeveloped for more than half a century, is ...
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Some patients in vegetative states have functioning minds. Keeping them alive may amount to ‘torture’

Jacob Appel | 
[Researchers] have convincingly demonstrated that a subset of individuals in persistent vegetative states have meaningfully functioning minds — even as ...
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‘We need it now’: Why precision medicine isn’t doing enough for children with cancer

Gwen Nichols | 
Precision medicine, the concept of giving the right treatment to the right patient at the right time, is flourishing in ...
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CBD fraud? Fate of controversial CBD industry could be decided by lawsuits alleging misleading marketing

Nicholas Florko | 
Since the Food and Drug Administration can’t figure out whether supplements that contain cannabidiol, the marijuana-adjacent oil known as CBD, are ...
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Rapid genetic sequencing marks key step in China’s efforts to contain mysterious new viral outbreak

Helen Branswell | 
Chinese scientists have recovered a previously unknown virus from an infected individual and generated a full genetic sequence of it, ...
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Second opinion? Google AI spots breast cancer more accurately than radiologists, in trial

Erin Brodwin | 
Researchers at Google, working alongside experts at Northwestern University and three British medical institutions, have created an AI model that ...
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Viewpoint: In 100 years, we’ll be honoring controversial CRISPR scientist He Jiankui

Josiah Zayner | 
When I saw the news that He Jiankui and colleagues had been sentenced to three years in prison for the first human ...
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Would the US prosecute a rogue scientist like China’s He Jiankui who illegally gene edited an embryo?

Josephine Johnston | 
13 months after He Jiankui announced that he had created the world’s first gene-edited babies, the Chinese scientist was sentenced to ...
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