Genetics suggest wheat gluten allergies mostly imaginary

wheat big

Some of the anti-glutenists argue that we havenโ€™t eaten wheat for long enough to adapt to it as a species.

Most of these assertions, however, are contradicted by significant evidence, and distract us from our actual problem: an immune system that has become overly sensitive.

For Dr. Bana Jabri, director of research at the University of Chicago Celiac Disease Center, itโ€™s the genetics of celiac disease that contradict the argument that wheat is intrinsically toxic.

A few years ago, Jabri and the population geneticist Luis B. Barreiro found that celiac-associated genes were abundant in the Middle Eastern populations whose ancestors first domesticated wheat.ย People who had them had some advantage compared with those who didnโ€™t.

Genes associated with autoimmune disorders, which amp up aspects of the immune response, helped people survive, thinks Barreiro.ย In essence, humanityโ€™s growing filth selected for genes that increase the risk of autoimmune disease, because those genes helped defend against deadly pathogens. Our own pestilence has shaped our genome.

Weโ€™re more sensitive to pollens (hay fever), our own microbes (inflammatory bowel disease) and our own tissues (multiple sclerosis).

Perhaps the sugary, greasy Western diet โ€” increasingly recognized as pro-inflammatory โ€” is partly responsible. Maybe shifts in our intestinal microbial communities, driven by antibiotics and hygiene, have contributed. Whatever the eventual answer, just-so stories about what we evolved eating, and what that means, blind us to this bigger, and really much more worrisome, problem: The modern immune system appears to have gone on the fritz.

Maybe we should stop asking whatโ€™s wrong with wheat, and begin asking whatโ€™s wrong with us.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Read full, original post:ย The Myth of Big, Bad Gluten

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosateโ€”the world's most heavily-used herbicideโ€”pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

Screenshot-2026-03-13-at-12.14.04-PM
The FDA wants to make many popular prescription drugs OTCโ€”a great idea. Hereโ€™s why itโ€™s unlikely to happen
Screenshot-2026-05-04-at-12.54.32-PM
How Utah became the countryโ€™s supplement capitalย  โ€” and a haven for unregulated, ineffective and fake products
Screenshot-2026-04-20-at-2.26.27-PM
Viewpoint โ€” Food-fear world: The latest activist scientists campaign: Cancer-causing additives
Screenshot-PM-24
Viewpoint: The herbicide glyphosate isnโ€™t perfect. Banning it would be far worse.
images
The never-ending GMO debate: Pros and cons
Screenshot-2026-05-01-at-11.56.24-AM
โ€˜Science moves forward when people are willing to think differentlyโ€™: Memories of DNA maverick Craig Venter
Screenshot-2026-04-30-at-2.19.37-PM
5 myths about summer dehydration that could damage your health โ€” or even kill you
Screenshot-2026-04-03-at-11.15.51-AM
Paraben panic: How a flawed study, media hype, and chemophobia convinced the public of the danger of one of the safest classes of preservatives
79d03212-2508-45d0-b427-8e9743ff6432
Viewpoint: The Casey Means hustleโ€”Wellness woo opportunism dressed up as medical wisdom
ChatGPT-Image-May-1-2026-02_20_13-PM
How RFK, Jr.โ€™s false vaccine claims are holding up $600 million to fight diseases in poor countries
bigstock opioids on chalkboard with rol
GLP podcast: 'Safe injection sites': enabling drug addiction or saving lives?
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.