Years of genomic research botched with errors thanks to Excel quirk

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A new paper has revealed the vast extent of errors in published genomics research,…[thanks to] an unfortunate quirk of Microsoft Excel…[Scientists] scanned 7,500 Excel files with gene lists accompanying 3,600 papers in 18 journals over a 10-year period. One-fifth of the files had easily identified errors, which is โ€œquite striking and a little bit embarrassing,โ€ says Mark Ziemann….

What happened? By default, Excel…convert some gene symbols to dates and numbers.ย For example, instead of writing out โ€œMembrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase,โ€ researchers have dubbed the gene MARCH1.

The thing is, thereโ€™s no excuse for data experts to be missing these errors with such regularity in the first place…It raises uncomfortable questions about the peer-review process at prestigious scientific journals, Ziemann says.

Still, although a one-fifth error rate may sound like a lot, itโ€™s not nearly as bad as in the business world, where some studies suggest that as many as 90% of spreadsheets in use at companies contain errors of one sort or another….

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Read full, original post:ย Years of genomics research is riddled with errors thanks to a bunch of botched Excel spreadsheets

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