Promising data has revealed a newย treatment for breast cancer and leukemia. It works by attacking cancer cellsโ ability to repair pathways (specifically, damaged pathways) in their DNA.
The teamย reports that a combination of an experimental, not-yet-approved drug and an epigenetic drug (calledย alazoparib and ย 5-azacytidine, respectively) resulted in a strong antitumor response.
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[Scientists] tested the drug therapy on breast cancer and leukemia โ cancers that depend on self-repairing mechanisms to grow mutated cells. Human breast cancer and leukemia cells, which were grownย in mice, faced the combination drug therapy. Ultimately, this resulted in tumors half the size of what either drug could do on its own, the paper notes.…
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The team tested the therapy on cancer with theย breast cancer susceptibility gene (BRCA), an inheritable gene that appears to increase theย riskย of breast cancer. And lead research Stephen Baylin says their study could lead to theย discovery of further treatments.
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The causes of cancer are not completely understood, and continuing research like this from Baylin gives hope to patientsย everywhere.
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