Scientists extract ‘near-complete’ HIV genome from 50-year-old tissue sample found ‘sitting in a drawer’

descubren que la pandemia de vih sida comenzo alrededor de
Image: Dirk Teuwen/Nature

Scientists extracted a near-complete HIV-1 genome from a lymph node that had been preserved in wax for more than 50 years. The sample stands as the oldest HIV-1 genome yet recovered, predating the previous oldest sample by a decade, the researchers reported July 1 on the preprint server bioRxiv

The HIV-1 virus was first discovered in 1983, 17 years after the contaminated lymph node was collected from a 38-year-old man in Democratic Republic of Congo.

Coauthor Michael Worobey and his colleagues discovered the lymph node, no larger than a fingernail, while combing through more than 1,600 tissue samples at the University of Kinshasa in search of HIV genome fragments. Among the plentiful samples, only the lymph node contained traces of the virus, according to The Atlantic. …

“It turns out that you can retrieve [RNA] more than 50 years later, even if the thing has been sitting in a drawer at ambient temperature. …” says Worobey

Related article:  3 experimental vaccines could be ‘game changer’ for HIV treatment

“Although its discovery doesn’t substantially alter our current model of the early genetic history of the AIDS pandemic, it does improve our confidence in conclusions previously drawn from modern and partial HIV gene sequences,” says Oliver Pybus, a professor of evolution and infectious diseases at the University of Oxford, in an interview with News-Medical.Net

Read full, original post: HIV-1 Genome Extracted from 1966 Tissue Sample

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend