AIDS vaccine: Why the COVID shot was developed so quickly but one for HIV remains elusive

AIDS vaccine: Why the COVID vaccine was developed so quickly but one for HIV remains elusive
Credit: Master Tux

Medical advances in AIDS include antiretroviral medications (ART) to suppress the virus and keep the disease under control; and pre-exposure prophylaxis (PrEP) drugs to prevent HIV transmission if taken correctly by uninfected people who see themselves at risk. Today almost 29 million of the world’s 38 million HIV-infected people have access to life-saving ART drugs, according to UNAIDS.

Mis- and disinformation are distorting science and public policy. Subscribe to our Daily and Weekly Digests for incisive coverage of ‘disruptive’ innovations in AI, agricultural biotechnology, food, chemicals, nuclear energy, vaccines, and other disruptive innovations.

And a vaccine against HIV remains frustratingly out of reach. That’s in contrast to the under one year it took to develop vaccines against COVID-19 that prevent severe disease, hospitalization and death in most cases.

So, if scientists can do it so quickly for COVID-19, why can’t they come up with a vaccine to prevent HIV?

A big part of the reason, says [AVAC executive director Mitchell] Warren, is the rate at which the AIDS virus mutates. “The world has tracked the variants of COVID,” he says. Those variants include Alpha, Beta, Delta, Omicron and subvariants. But HIV is much more variable. “There are more variants of HIV in one person’s body within days after infection than all the variants of COVID.” That means that even as a vaccine is being developed to attack HIV, the virus may be mutating out of its reach.

This is an excerpt. Read the full article here

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

Crumbling MAHA Stage Portrait
Cataloging the RFK Jr.-MAHA crushing midterm collapse
Microscopic IVF Egg Injection
With technical barriers to human embryo editing falling, ethical concerns escalate
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
Blue Checklist in Centered Hand
Viewpoint: From Medicaid cuts to MAHA-backed anti-vaccine and chemical hysteria, voters reject Republicans’ science-skeptical agenda
Hipster eugenics: better babies for billionaires
Viewpoint: “Positive eugenics”: Reviving a movement reviled and condemned for a century
Smiling-Woman-Over-Teal-Abstract-Shapes
Viewpoint: RFK Jr.’s latest foray into junk science: Even Kennedy’s hand-picked NIH director balks at appointment of crackpot mental health director
Picture1
Viewpoint: How badly is the U.S. food-safety net fraying? FDA’s bungled handling of the tainted lettuce crisis deepens concerns over cuts to disease tracking and response
Reaching Through the Woven Sky
Challenging genetic modification rejectionists: Our evolving food system has relied on science for thousands of years
Bayer Crop Circle in Golden Wheat
Making fertilizer from thin air: Bayer’s gene-editing innovation could dramatically cut chemical fertilizer use in growing food
Screenshot-2026-10-29-at-11.18.34-AM
Viewpoint: ‘Just the flu’: Skipping your child’s flu shot could be a fatal mistake
Screenshot 2026-11-04 at 12.02
Ever wonder why AI can so easily be duped into manufacturing health misinformation?    
Neon Genome_ Fetal Dreamscape
The race to genetically engineer babies
Screenshot-2026-11-02-at-11.34.28-AM
Farmers are collateral damage in the PFAS “forever chemicals” crossfire. Here’s what they need to know.
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.