Genetics suggest wheat gluten allergies mostly imaginary

wheat big

Some of the anti-glutenists argue that we havenโ€™t eaten wheat for long enough to adapt to it as a species.

Most of these assertions, however, are contradicted by significant evidence, and distract us from our actual problem: an immune system that has become overly sensitive.

For Dr. Bana Jabri, director of research at the University of Chicago Celiac Disease Center, itโ€™s the genetics of celiac disease that contradict the argument that wheat is intrinsically toxic.

A few years ago, Jabri and the population geneticist Luis B. Barreiro found that celiac-associated genes were abundant in the Middle Eastern populations whose ancestors first domesticated wheat.ย People who had them had some advantage compared with those who didnโ€™t.

Genes associated with autoimmune disorders, which amp up aspects of the immune response, helped people survive, thinks Barreiro.ย In essence, humanityโ€™s growing filth selected for genes that increase the risk of autoimmune disease, because those genes helped defend against deadly pathogens. Our own pestilence has shaped our genome.

Weโ€™re more sensitive to pollens (hay fever), our own microbes (inflammatory bowel disease) and our own tissues (multiple sclerosis).

Perhaps the sugary, greasy Western diet โ€” increasingly recognized as pro-inflammatory โ€” is partly responsible. Maybe shifts in our intestinal microbial communities, driven by antibiotics and hygiene, have contributed. Whatever the eventual answer, just-so stories about what we evolved eating, and what that means, blind us to this bigger, and really much more worrisome, problem: The modern immune system appears to have gone on the fritz.

Maybe we should stop asking whatโ€™s wrong with wheat, and begin asking whatโ€™s wrong with us.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Read full, original post:ย The Myth of Big, Bad Gluten

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