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Chasing a cure for narcolepsy—and why it should be a priority

Henry Nicholls | 
For the first 20 years of his life, Henry Nicholls had a healthy relationship with sleep. Shortly after his 21st ...
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Migraine relief: First drug in 20 years that can prevent and cut in half length of attacks

A new migraine drug that can halve the length of attacks has been hailed as “the start of real change” ...
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Bacterial DNA used in innovative Hepatitis B vaccines

Paul Offit | 
Two hepatitis B virus vaccines are currently on the market. Earlier this month, however, the Food and Drug Administration licensed ...
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Hepatitis B treatable with unique new strategy—using bacterial DNA

Paul Offit | 
Two hepatitis B virus vaccines are currently on the market. Earlier in November, however, the Food and Drug Administration licensed ...
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Synaesthesia: For those who lose their sight, colors can have sound

Vanessa Potter | 
Vanessa Potter lost her sight. As she recovered, her senses mingled – hearing and touch changed the way she saw ...
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How gene therapy could help fight methamphetamine addiction

Emily Mullin | 
Gene therapy, which modifies a person’s DNA, has long been thought of as a way to treat genetic diseases—and, more recently, ...
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Food, vaccines and medicine: How plant scientists are changing the world

Erica Hawkins | 
[Editor's note: Erica Hawkins is a PhD student at the John Innes Centre and the University of East Anglia studying medicinal plant ...
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Checkpoint inhibitors fight cancer–but can have nasty side effects

Jennifer Couzin-Frankel | 
Yale University immunologist Kevan Herold spoke about a few of his newest diabetes patients to an unlikely audience: oncologists and ...
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Could ‘superantibiotics’ save us from rising drug resistance?

David Cox | 
The need for new classes of antibiotics has repeatedly been emphasised, with researchers turning to some of the most extreme environments on ...
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CRISPR at home: Is it really that easy to hack DNA?

Annie Sneed | 
I am not a DIY scientist, much less a professional scientist. You won’t find me swabbing my cheek cells for ...
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‘Young blood’ infusions may boost cognitive abilities of Alzheimer’s patients

Alison Abbott | 
The first controlled, but controversial and small, clinical trial of giving young blood to people with dementia has reported that ...
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Gene circuit triggers immune system to battle cancer

Steve Hill | 
A research team at MIT has used synthetic biology to create a gene circuit that triggers the immune system to ...
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Bioethics: What are CRISPR’s real threats and rewards?

[S]cientists from the University of Wisconsin-Madison and the Morgridge Institute for Research participated in an international think tank this month ...
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When genetic engineering came of age: World’s first GMO—GE insulin—approved 35 years ago

Henry Miller | 
It has been 35 years since genetically engineered insulin was approved by the FDA in a process that was quick ...
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CAR-T engineering of patients’ own T cells for cancer therapy gains traction

Elie Dolgin | 
The strategy of engineering patients' own T cells for cancer therapy got two major endorsements in late August, one financial ...
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Unapproved stem cell therapy leaves elderly women blind

Sarah Zhang | 
[E]ye doctors based primarily at the Bascom Palmer Eye Institute in Miami had published a widely covered report describing three eerily similar cases: ...
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Time to stop treating men and women the same when it comes to drug treatments

Ben Locwin | 
Studies have shown that males and females metabolize drugs differently, suggesting we should be spending more time studying those differences ...
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Genetically modified skin grafts could monitor glucose, end needle sticks for diabetes

Daisy Yuhas | 
Painful and inconvenient, needle sticks are part of daily life for many people with diabetes. Wouldn’t it be great if ...
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Growing cancer drugs in chicken eggs could lower costs by 90%

Puja Bhattacharjee | 
Researchers in Japan may have found a way to produce cheaper drugs that could be used to treat a range ...
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Modeling human tumors in mice can be problematic—here’s why

John Timmer | 
[A] new study [read full study] suggests that an unfortunate side effect of ... evolutionary changes is that human tumors are ...
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Drug that ‘mutes’ defective genes that cause nerve disorders effective in trials

Meghana Keshavan | 
A crucial, late-stage clinical trial showed that the [nerve disorder drug patisiran] works—and that it’s safe. And now the biotech company ...
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Biologics joining fight against asthma

Josh Bloom | 
Should you be unfortunate enough to suffer from asthma, things are looking up. There are new biological therapies out there that ...
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Synthetic bionics: E. coli pills could boost body’s ability to absorb ammonia in the gut

Antonio Regalado | 
Synlogic of Cambridge, Massachusetts, the company behind the unusual study, is testing what it calls “synthetic biotics,” or bacteria engineered ...
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CRISPR ear injections repair genetic hearing loss in mice

Antonio Regalado | 
We all know that CRISPR is the next big thing in gene-editing treatments. But how do you get the versatile genetic scissors ...
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Male contraceptive breakthrough? ‘Birth control gel’ ready for couples study

Dina Maron | 
The creators of a male birth control gel designed to inhibit sperm production—while maintaining healthy testosterone levels in the bloodstream—will ...
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Edible ‘CRISPR pill’ could make harmful bacteria self-destruct

Emily Mullin | 
As resistance to antibiotics grows in the U.S., researchers are looking for new ways to fight germs like Clostridium difficile, a ...
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Insomnia cures: Do drug remedies provide the kind of sleep that our brain needs?

Ben Locwin | 
People spend billions on sleep remedies. The act of sleep and artificially assisting sleep are not on the whole a ...
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