Human Gene Editing
Single-dose CRISPR gene editing technology helps train patients’ immune systems to fight cancer
For the first time, researchers have used CRISPR technology to substitute genes in patients’ immune cells to treat cancer. Participants ...
Poor cholesterol? A gene-edited solution could lower ‘bad’ LDL and reduce heart disease risk
While a poor diet, stress, lack of exercise, and other lifestyle factors can lead to cholesterol problems, genetic factors also ...
Children born during the great depression aged rapidly later in life. Here’s how trauma can affect you before you’re even born
The worst recession in US history shaped how well people would age — before they were even born. Researchers have ...
Viewpoint: Gene editing is revolutionizing medicine — but it opens a Pandora’s box of ethical questions
Genetic engineering or genetic modification has long been a headline grabber, often framed in a negative light. However we need ...
Viewpoint: ‘What’s the biological equivalent of an atomic bomb’? Here’s how the gene editing revolution could go astray
We now sequence the genes of people, animals, plants and tumors routinely. We’re starting to edit DNA, not only in ...
CRISPR co-creator Jennifer Doudna looks back on the best and worst parts of gene editing’s first ten years
In a candid conversation with GEN Senior Science Writer Julianna LeMieux during “The State of Biotech” forum, Doudna discussed a ...
‘We are out on the far edge of experimentation’: Lone volunteer in Duchenne muscular dystrophy CRISPR gene editing study dies
The lone volunteer in a unique study involving a gene-editing technique has died, and those behind the trial are now ...
Gene therapy update: More than 2,000 treatments are in development worldwide as revolution spreads to low- and middle-income countries
Gene therapy is at the forefront of modern medicine. By making precise changes to the human genome, these sophisticated technologies ...
Drawing a line: European Convention upholds ban on heritable human genome editing
The Council of Europe’s Convention on Human Rights and Biomedicine, better known as the Ovideo Convention, explicitly bans heritable human ...
‘Just because we can do it, should we?’ How CRISPR co-creator Jennifer Doudna is furthering the discussion over the ethics of human genome editing
In 2012, Jennifer Doudna, then a relatively unknown biochemist at the University of California Berkeley, published a paper with Emmanuelle Charpentier ...
Podcast: ‘Regenerative’ farming—a green fad; Gene-edited bacteria destroy tumors; Banana-flavored beer
So-called "regenerative" farming is gaining traction as a method of sustainable food production. Does it live up to the hype ...
‘Obesity is way more complex than we thought’: Risk of being overweight likely influenced by what happened in the womb
Obesity can seriously compromise a person’s physical and mental health. It is definedTrusted Source as “abnormal or excessive fat accumulation ...
CRISPR cryptography: Making the world safer from gene-editing research gone awry
Evolution is Kevin Esvelt’s passion: how it works in nature, how we can direct it, and how it can go ...
New treatments for rare, inherited childhood diseases? CRISPR sheep help advance research
A flock of gene-edited sheep has been used by scientists to pinpoint a promising treatment for a lethal inherited brain ...
A CRISPR cure for HIV? Gene-editing technology may be able stop viral replication in its tracks and wipe out infections
In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to ...
‘Near-limitless CRISPR therapies’: This drug delivery breakthrough helps gene editing technology infiltrate cells
A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future ...
Gene therapy approvals now at four with treatments for inherited anemia and degenerative brain condition — but costs are stratospheric. Why?
The FDA recently approved two gene therapies with hefty price tags, the first for an inherited anemia and the second ...
10-year CRISPR anniversary: How gene editing revolutionized medicine, and what lies ahead
Ten years ago, a little-known Science paper authored by Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D., proposed using CRISPR/Cas9 for gene editing ...
‘When we exercise, we’re not just doing it for ourselves’: Why going on a run today could benefit your future grandkids
Exercising now is good for you. But could it also be good for your future children and grandchildren? ...
CRISPR co-creator Emmanuelle Charpentier: ‘Studying microbes can solve some of the biggest problems facing humanity, including how our metabolisms and brains work’
In early September, CRISPR co-creator Emmanuelle Charpentier traveled to Yerevan, Armenia to be one of the main speakers at the ...
New reversible gene-editing technique may be safer and more reliable than standard CRISPR
Chinese researchers say they have developed a new gene-editing tool that is more efficient and safer because it does not ...
Moonshot genomics: How CRISPR is opening the door to reshaping life itself
It’s a moonshot idea. If the genome is a book, gene editing is like copy editing—changing a typo here and ...
Could there ever be a vaccine for breast cancer?
Triple-negative breast cancer, about 10% of all breast cancers, is one of the most aggressive and deadliest forms of this ...
Novel gene therapy study offers hope for definitive colorblindness cure
Researchers from the University College London (UCL) used gene therapy to partly restore the function of the retina's cone receptors ...
Duchenne muscular dystrophy (DMD): Background on the first personalized CRISPR therapy approved for trial
The FDA has given the greenlight to test the first personalized CRISPR therapy, which was developed specifically to treat one ...
$2.8 million Zynteglo gene therapy: Bluebird sets price on one-time beta-thalassemia treatment replacing red blood cell transfusions
Zynteglo has become the first cell-based gene therapy to be approved in the US, getting the nod from the FDA ...
Why resurrecting near-replicas of extinct woolly mammoths might work
Woolly mammoths, the iconic giants of the last ice age, went extinct around 4,000 years ago. But one company is ...
