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Developing a ‘kill switch’ to make CRISPR gene editing more precise—and safer

Elie Dolgin |
[Microbiologists] stumbled onto tools now known as anti-CRISPRs. These proteins serve as the rocks to CRISPR’s molecular scissors. And soon, ...
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Quest to understand sense of touch could lead to new treatments for chronic pain

Amber Dance |
If she wasn’t looking at her limbs, the girl didn’t seem to have any clue where they were. She lacked ...
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‘Search and destroy’: Precision stem cell treatments could be safer against blood cancers

Heidi Ledford |
Scientists are experimenting with ways to selectively target the body’s blood-making cells for destruction. Early studies in animals and people ...
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‘De novo genes’: How natural selection creates new genes from nothing

Adam Levy |
In the depths of winter, water temperatures in the ice-covered Arctic Ocean can sink below zero. That’s cold enough to ...
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Emerging field of ‘social genomics’ comes with ethical, societal risks: ‘Who’s going to benefit?’

David Adam |
By looking at the genomes of people living in former coal-mining areas, [geneticist Abdel Abdellaoui] has found genetic signatures associated ...
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Researchers retract study questioning long-term health of China’s controversial CRISPR babies

Ewen Callaway |
A study that raised questions over the future health of the world’s first gene-edited babies has been retracted because of ...
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Japan’s quest to be world leader in regenerative medicine sparks surge in questionable stem cell treatments

David Cyranoski |
In the United States, authorities have grappled with a surge of clinics selling therapies that are unsupported by evidence and, ...
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‘Using Nature’s Shuttle’: Judith M. Heimann’s fascinating new book about how scientists learned to create genetically modified crops

Jonathan D.G. Jones |
Judith M. Heimann’s recent book [Using Nature's Shuttle] provides a thoroughly engaging account of how [the mystery of plant crown ...
First real anti-aging drug on the horizon? Common drugs turned back body’s epigenetic clock 2.5 years in small trial

First real anti-aging drug on the horizon? Common drugs turned back body’s epigenetic clock 2.5 years in small trial

Alison Abbott |
A small clinical study in California has suggested for the first time that it might be possible to reverse the ...
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Japanese woman receives first artificial cornea created from reprogrammed stem cells

David Cyranoski |
A Japanese woman in her forties has become the first person in the world to have her cornea repaired using ...
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CRISPR creates ‘smart’ hydrogels that could lead to therapies capable of fighting multiple infections, diseases

Ewen Callaway |
Is there anything CRISPR can’t do? Scientists have wielded the gene-editing tool to make scores of genetically modified organisms, as ...
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‘From quackery to established science’: Here’s what’s going on with promising anti-aging research

Shelly Fan |
It’s hard to pinpoint the exact moment anti-aging research morphed from quackery to an established science. Some say it’s 1939, ...
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‘Built to forget’: Why memory lapses are good for our brains

Lauren Gravitz |
Until about ten years ago, most researchers thought that forgetting was a passive process in which memories, unused, decay over ...
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Infographic: Here’s how gene drives would fight mosquitos, malaria

Megan Scudellari |
Gene drives have rapidly become a routine technology in some laboratories; scientists can now whip up a drive in months ...
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Scientific, social and ethical barriers must be overcome before the world is ready for CRISPR babies, researchers say

Heidi Ledford |
Nature asked researchers and other stakeholders what hurdles remain before heritable gene editing could become acceptable as a clinical tool ...
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Another CRISPR controversy brews as Russian scientist announces plans to produce gene-edited babies

David Cyranoski |
A Russian scientist says he is planning to produce gene-edited babies, an act that would make him only the second ...
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This tech start-up wants to ‘hack’ efforts to save endangered species, ecosystems

Lisa Palmer |
After an unorthodox career in science that has included setting up a national park in an active war zone in ...
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Short or tall? Genes account for 79% of height differences, study shows

Linda Geddes |
Since the human genome was sequenced nearly two decades ago, researchers have struggled to fully identify the genetic factors responsible [for ...
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Pushing for greater diversity in genetic databases by ending ‘cycle of disengagement’

Giorgia Guglielmi |
For the past 30 years, human genomics has made exciting advances in reconstructing population history and identifying which genes make ...
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Turning brain signals into speech using artificial intelligence moves closer to reality

Giorgia Guglielmi |
In an effort to provide a voice for people who can’t speak, neuroscientists have designed a device that can transform ...
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Do men and women feel pain differently?

Amber Dance |
Pain researchers are opening their eyes to the spectrum of responses across sexes. Results are starting to trickle out, and ...
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‘Paradigm shifting’: Monthly injections could replace daily pills for HIV patients

Amy Maxmen |
Long-acting medicines have proved as effective as daily pills in preventing HIV from replicating, according to results from twin trials ...
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China tightens gene-editing regulations in wake of CRISPR baby scandal

David Cyranoski |
China’s health ministry has issued draft regulations that will restrict the use of gene editing in humans, just three months ...
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Among questions lingering after CRISPR-babies controversy: When will it happen again?

David Cyranoski |
In the three months since He Jiankui announced the birth of twin girls with edited genomes, the questions facing the ...
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‘Good Reasons for Bad Feelings’: Understanding evolution’s role in anxiety, depression and making us human

Adrian Woolfson |
[In] the thought-provoking Good Reasons for Bad Feelings, [evolutionary] psychiatrist Randolph Nesse offers insights that radically reframe psychiatric conditions. In his ...
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Who were the Denisovans? This Siberian cave could offer answers

Ewen Callaway |
Samantha Brown didn’t have high hopes when she opened the ziplock bag containing some 700 shards of bone. It would ...
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Challenging Nature’s decision to run a stem cell advertisement portrayed as research

Michael Hiltzik |
Readers of Nature, one of the world’s most important scientific journals, might have been struck recently by an audacious claim ...
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