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Viewpoint: Promise of genomics and precision medicine a ‘wave of hype without substance’

An undeclared civil war is breaking out in biomedicine. On one side is precision medicine, with its emphasis on tailoring treatments ...
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‘Headed down the wrong road’: The quest for precision medicine distracts us from what already works

The dominance of genomics in biomedical research today is driven by scientific theory and opportunity, but it is pushing science ...
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‘We need it now’: Why precision medicine isn’t doing enough for children with cancer

Precision medicine, the concept of giving the right treatment to the right patient at the right time, is flourishing in ...
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Podcast: How precision, customized medicine is reshaping health care

For all the life-saving pharmaceuticals, surgeries and devices it provides, modern medicine is still rather imprecise. Chemotherapy drugs, for instance, ...
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‘All of Us’: NIH precision medicine study will share genetic data with participants, offer counseling

The nearly 200,000 Americans who have trusted federal scientists with their DNA, their medical records, and detailed behavioral surveys will ...
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Precision medicine dampened by lack of diversity in gene research pool

[Anthropologist and bioethicist Sandra Soo-Jin Lee] recently wrote about ethics in personalized medicine research for Science magazine, and we spoke ...
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Why the promise of precision drug treatments is blunted by a lack of racial diversity in genetics research

A lack of racial and ethnic diversity in pharmacogenomic research is raising questions about whether poorly represented groups are being ...
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How ‘smart toilets’ and other technologies could help detect cancer before it’s too late

I believe we should be more aggressively pursuing precision health: ways to prevent disease and, when that isn’t possible, intercept and ...
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Viewpoint: It’s time for a debate on precision medicine and its failed promises

Although some niche applications have been found for precision medicine, and gene therapy is now becoming a reality for a ...
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Using genetic tests to tailor antipsychotic treatments to individual patients

Scientists are tapping individuals’ genetic profiles to learn which patients will respond to antipsychotic medication for schizophrenia. The pursuit is ...
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Precision medicine for dogs? Silicon Valley startup wants to make it happen

When pet dogs are diagnosed with cancer, they typically get surgery, chemotherapy, or radiation — that is, of course, if ...
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Which contraceptive is best for you? Precision medicine could provide the answer

Approximately 900 million women around the world use contraceptives. It’s a shame that, even with the best available evidence and resources, an ...
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Geneticist Carlos Bustamante’s effort to make DNA databases less white

In the 15 years since the Human Genome Project first exposed our DNA blueprint, vast amounts of genetic data have ...
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Failure of race-based medicine? We aren’t accounting for the unique genetics of biracial and multiracial populations

For several decades in modern medicine history, human race has been used as a constant variable to predict and/or determine ...
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In order to thrive, precision medicine requires ‘novel business solutions’

Oncology currently leads the way in precision medicine advancements, but its forward progress is slowed by inefficiencies such as clinical ...
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Viewpoint: Precision medicine promises a lot, but has delivered little

Doctors and hospitals love to talk about the patients they’ve saved with precision medicine, and reporters love to write about ...
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Viewpoint: There’s danger in overselling the benefits of routine DNA sequencing

For decades the potential of stem cells to cure all disease was promised. Today’s reality is that the few worthy ...
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Fighting deadly adverse drug reactions through precision medicine

Lee Tan, a 41-year-old marketing professional and copywriter in Vancouver, Canada, was diagnosed with high blood pressure three years ago ...
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Gene-editing advances put us at the dawn of a revolution in medicine

So much of the public's attention is focused on the use of genetic engineering in the crops that our farmers ...
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Genetics for public health: A lost cause?

Its power for discovering rare diseases is well proven. But genetics’ impact on public and preventative health has a long ...
DNA Testing Can Be Done Discreetly Without Cooperating Donors

One family’s story of misdiagnosis reveals harsh reality: DNA tests aren’t perfect

Personal genetic tests and precision medicine are becoming increasingly popular tools but caution is appropriate. The technology is still evolving ...
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Will epigenetics play central role in advancement of precision medicine?

For many treatments it remains to be proven whether a drug's epigenetic actions, rather than another mechanism such as stimulation ...
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How many genomes is enough for US Precision Medicine Initiative?

FDA head says Precision Medicine Initiative should sequence one in every four Americans. Where will that money come from? And ...
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Can GMOs cure cancer? Genetically engineered algae found to kill cancer cells

Scientists have genetically engineered algae, transforming them into targeted drug delivery systems to target cancer. It's worked in the lab ...
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Precision medicine’s cost challenges: Are there lower tech alternatives?

Precision medicine is leading to cures but at high cost to healthcare systems. But there are emerging examples of lower-tech ...
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Blood test can prevent suicide? How to prevent “biomarker porn”

Biomarker testing is the shiny new thing. Some scientists claim they can predict complex mental disorders. It would be nice ...
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Precision medicine–Next new thing or over hyped bust? (Or both?)

Precision medicine struggles to fulfill its promise as a next generation solution to disease prevention ...
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Designer viruses and precision medicine: New findings for the future of gene therapies

Precision and personalized medicine have at their heart the promise of targeting diseases with specialized therapies specific to certain types ...