Gene therapy that reboots body’s immune cells to fight non-Hodgkin’s lymphoma approved by FDA

CANCERkite master
Cells taken from cancer patients are genetically engineered to fight cancer at a Kite processing facility. Credit Kite Pharma

The Food and Drug Administration on [October 19] approved the second in a radically new class of treatments that genetically reboot a patient’s own immune cells to kill cancer.

The new therapy, Yescarta, made by Kite Pharma, was approved for adults with aggressive forms of a blood cancer, non-Hodgkin’s lymphoma, who have undergone two regimens of chemotherapy that failed.

The treatment, considered a form of gene therapy, transforms the patient’s cells into what researchers call a “living drug” that attacks cancer cells. It is part of the rapidly growing field of immunotherapy, which uses drugs or genetic tinkering to turbocharge the immune system to fight disease. In some cases the treatments have led to long remissions.

The first cell-based cancer treatment — Kymriah, made by Novartis — was approved in August for children and young adults with an aggressive type of acute leukemia.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: F.D.A. Approves Second Gene-Altering Treatment for Cancer

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