Video: Lab-grown human heart tissue beats ‘like the real thing’

be d d deb
Image credit: First Post

A tiny pulsing strip of muscle could help save the lives of 33 million people.

That’s how many people suffer from atrial fibrillation, the most common type of irregular heartbeat. Scientists have yet to invent an effective treatment for it, partly due to the difficulty in isolating heart muscle cells and then keeping them viable long enough to develop and test new drugs.

Now, a team of German researchers has grown strips of human heart tissue in the lab. Not only does the tissue express genes and respond to drugs in ways that closely resembles those of naturally derived atrial heart tissue — but it also beats like the real thing.

Related article:  "Home brewed morphine" from genetically engineered yeast? What did the media get wrong?

According to the German team’s study, which was published [November 8] in the journal Stem Cell Reports, the researchers created their human atrial heart tissue by treating hiPCSs with all-trans retinoic acid, a substance made from vitamin A that helps cells grow.

Rather than culture their cells to grow in a flat, two-dimensional layer, though, the team then coaxed them to grow into 3D strips of muscle tissue, a form more similar to actual atrial heart muscle.

The researchers are now focused on figuring out how they can use their lab-grown heart tissue to develop treatments for atrial fibrillation.

Read full, original post: See Lab-Grown Human Heart Tissue Beat Like a Real Heart

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend