About seven years ago, researchers at the US DNA sequencing company Illumina started to notice something odd. A new blood test it ran on 125,000 expectant mothers looking for genetic abnormalities such as Down syndrome in their foetuses returned some extremely unexpected signals in 10 cases. Chillingly, it dawned on them that the abnormal DNA they were seeing wasn’t from the foetuses but was, rather, undiagnosed cancer in the mothers. Cancers of different types were later confirmed in all 10.
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[Illumina’s partner company] Grail is on a quest to detect multiple types of cancer before symptoms, via a single, simple blood test. The test looks at cell-free plasma to find fragments of so-called circulating tumour DNA (ctDNA) sloughed off by cancer cells.Related article: Was life on Earth 'just a lucky accident’? Next Mars mission will drill for answers
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