Unraveling the mystery of why cancer is soaring among people under 50

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Worldwide, the number of new early-onset cancer cases is projected to rise by 31% and deaths by 21% by 2030, a new study found. Credit: Rhoda Baer/Wikimedia Commons

Cancer is hitting more young people in the U.S. and around the globe, baffling doctors. Diagnosis rates in the U.S. rose in 2019 to 107.8 cases per 100,000 people under 50, up 12.8% from 95.6 in 2000, federal data show. A studyย in BMJ Oncologyย last year reported a sharp global rise in cancers in people under 50, with the highest rates in North America, Australia and Western Europe.

Doctors are racing to figure out what is making them sick, and how to identify young people who are at high risk.

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Deep-fried and highly processed foods have beenย implicated in other studiesย of early onset colorectal cancer, while diets with fiber, fruits and vegetables likely lower risks. Cancers including colorectal, breast and pancreatic have been tied to obesity, and studiesย supportย a link between excess weight and some early onset cancers.

Some doctors suspect that cancer-causing exposures might have started during patientsโ€™ childhoods, something that is difficult to trace. Unlike when smoking drove up lung cancer deaths in the 20th century, doctors suspect there isnโ€™t a single carcinogen responsible for the current trends.

โ€œIs it part of a larger trend of, are we just getting unhealthier?โ€ said Dr. Sachin Apte, chief clinical officer at Huntsman Cancer Institute at the University of Utah.

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